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Journal Articles Journal of Infectious Diseases Year : 2020

Changing Contact Patterns Over Disease Progression: Nipah Virus as a Case Study

Peter Daszak
Stephen Luby
  • Function : Author

Abstract

Abstract Contact patterns play a key role in disease transmission, and variation in contacts during the course of illness can influence transmission, particularly when accompanied by changes in host infectiousness. We used surveys among 1642 contacts of 94 Nipah virus case patients in Bangladesh to determine how contact patterns (physical and with bodily fluids) changed as disease progressed in severity. The number of contacts increased with severity and, for case patients who died, peaked on the day of death. Given transmission has only been observed among fatal cases of Nipah virus infection, our findings suggest that changes in contact patterns during illness contribute to risk of infection.

Dates and versions

pasteur-04095367 , version 1 (11-05-2023)

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Kyu Han Lee, Birgit Nikolay, Hossain Sazzad, M Jahangir Hossain, A Khan, et al.. Changing Contact Patterns Over Disease Progression: Nipah Virus as a Case Study. Journal of Infectious Diseases, 2020, 222 (3), pp.438-442. ⟨10.1093/infdis/jiaa091⟩. ⟨pasteur-04095367⟩
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