Article Dans Une Revue ISME Communications Année : 2024

Diversity of Bathyarchaeia viruses in metagenomes and virus-encoded CRISPR system components

Résumé

Bathyarchaeia represent a class of archaea common and abundant in sedimentary ecosystems. Here we report 56 metagenome-assembled genomes of Bathyarchaeia viruses identified in metagenomes from different environments. Gene sharing network and phylogenomic analyses led to the proposal of four virus families, including viruses of the realms Duplodnaviria and Adnaviria, and archaea-specific spindle-shaped viruses. Genomic analyses uncovered diverse CRISPR elements in these viruses. Viruses of the proposed family “Fuxiviridae” harbor an atypical Type IV-B CRISPR-Cas system and a Cas4 protein that might interfere with host immunity. Viruses of the family “Chiyouviridae” encode a Cas2-like endonuclease and two mini-CRISPR arrays, one with a repeat identical to that in the host CRISPR array, potentially allowing the virus to recruit the host CRISPR adaptation machinery to acquire spacers that could contribute to competition with other mobile genetic elements or to inhibit host defenses. These findings present an outline of the Bathyarchaeia virome and offer a glimpse into their counter-defense mechanisms.

Domaines

Virologie
Fichier principal
Vignette du fichier
Duan2024ISMECommun.pdf (3.97 Mo) Télécharger le fichier
Origine Publication financée par une institution
Licence

Dates et versions

pasteur-04447359 , version 1 (08-02-2024)

Licence

Identifiants

Citer

Changhai Duan, Yang Liu, Ying Liu, Lirui Liu, Mingwei Cai, et al.. Diversity of Bathyarchaeia viruses in metagenomes and virus-encoded CRISPR system components. ISME Communications, 2024, 4 (1), pp.ycad011. ⟨10.1093/ismeco/ycad011⟩. ⟨pasteur-04447359⟩

Collections

PASTEUR CNRS
18 Consultations
19 Téléchargements

Altmetric

Partager

More