Interactions between vector competence to chikungunya virus and resistance to deltamethrin in Aedes aegypti laboratory lines? - Institut Pasteur Accéder directement au contenu
Article Dans Une Revue Medical and Veterinary Entomology Année : 2022

Interactions between vector competence to chikungunya virus and resistance to deltamethrin in Aedes aegypti laboratory lines?

Résumé

The urban mosquito species Aedes aegypti is the main vector of arboviruses worldwide. Mosquito control with insecticides is the most prevalent method for preventing transmission in the absence of effective vaccines and available treatments; however, the extensive use of insecticides has led to the development of resistance in mosquito populations throughout the world, and the number of epidemics caused by arboviruses has increased. Three mosquito lines with different resistance profiles to deltamethrin were isolated in French Guiana, including one with the I1016 knock-down resistant allele. Significant differences were observed in the cumulative proportion of mosquitoes with a disseminated chikungunya virus infection over time across these lines. In addition, some genes related to resistance (CYP6BB2, CYP6N12, GST2, trypsin) were variably overexpressed in the midgut at 7 days after an infectious bloodmeal in these three lines. Our work shows that vector competence for chikungunya virus varied between Ae. aegypti laboratory lines with different deltamethrin resistance profiles. More accurate verification of the functional association between insecticide resistance and vector competence remains to be demonstrated.

Dates et versions

pasteur-04124922 , version 1 (11-06-2023)

Identifiants

Citer

Lanjiao Wang, Albin Fontaine, Pascal Gaborit, Amandine Guidez, Jean Issaly, et al.. Interactions between vector competence to chikungunya virus and resistance to deltamethrin in Aedes aegypti laboratory lines?. Medical and Veterinary Entomology, 2022, 36 (4), pp.486-495. ⟨10.1111/mve.12593⟩. ⟨pasteur-04124922⟩
15 Consultations
2 Téléchargements

Altmetric

Partager

Gmail Facebook X LinkedIn More