Evidence of Lymphocytic Choriomeningitis Virus (LCMV) in Domestic Mice in Gabon: Risk of Emergence of LCMV Encephalitis in Central Africa - Institut Pasteur Access content directly
Journal Articles Journal of Virology Year : 2015

Evidence of Lymphocytic Choriomeningitis Virus (LCMV) in Domestic Mice in Gabon: Risk of Emergence of LCMV Encephalitis in Central Africa

Abstract

ABSTRACT Lymphocytic choriomeningitis virus (LCMV) can cause acute fatal disease on all continents but was never detected in Africa. We report the first detection of LCMV RNA in a common European house mouse ( Mus musculus domesticus ) in Africa. Phylogenetic analyses show a close relationship with North American strains. These findings suggest that there is a risk of the appearance of LCMV acute encephalitis cases. This is a perfect example of virus dissemination by its natural host that may have dramatic public health consequences.

Dates and versions

pasteur-03516026 , version 1 (07-01-2022)

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Nadine N′dilimabaka, Nicolas Berthet, Virginie Rougeron, Joa Braïthe Mangombi, Durand Patrick, et al.. Evidence of Lymphocytic Choriomeningitis Virus (LCMV) in Domestic Mice in Gabon: Risk of Emergence of LCMV Encephalitis in Central Africa. Journal of Virology, 2015, 89 (2), pp.1456-1460. ⟨10.1128/JVI.01009-14⟩. ⟨pasteur-03516026⟩
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