Breaching the phagosome, the case of the tuberculosis agent - Institut Pasteur Access content directly
Journal Articles Cellular Microbiology Year : 2021

Breaching the phagosome, the case of the tuberculosis agent

Abstract

The interactions between microbes and their hosts are among the most complex biological phenomena known today. The interaction may reach from overall beneficial interaction, as observed for most microbiome/microbiota related interactions to interaction with virulent pathogens, against which host cells have evolved sophisticated defence strategies. Among the latter, the confinement of invading pathogens in a phagosome plays a key role, which often results in the destruction of the invader, whereas some pathogens may counteract phagosomal arrest and survive by gaining access to the cytosol of the host cell. In the current review, we will discuss recent insights into this dynamic process of host-pathogen interaction, using Mycobacterium tuberculosis and related pathogenic mycobacteria as main examples.
Fichier principal
Vignette du fichier
Breaching the phagosome_revised-clean-final-final.pdf (491.85 Ko) Télécharger le fichier
Figure-1 Review CMI2021.pdf (376.74 Ko) Télécharger le fichier
Figure-1 Review CMI2021.pptx (65.32 Ko) Télécharger le fichier
Origin : Files produced by the author(s)

Dates and versions

pasteur-03413281 , version 1 (05-11-2021)

Licence

Attribution - NonCommercial

Identifiers

Cite

Roxane Simeone, Fadel Sayes, Emeline Lawarée, Roland Brosch. Breaching the phagosome, the case of the tuberculosis agent. Cellular Microbiology, 2021, 23 (7), pp.e13344. ⟨10.1111/cmi.13344⟩. ⟨pasteur-03413281⟩
56 View
43 Download

Altmetric

Share

Gmail Facebook Twitter LinkedIn More