A High-Resolution Microsatellite Map of the Mouse Genome
Michael Rhodes
(1)
,
Richard Straw
(1)
,
Supem Fernando
(1)
,
Andrew Evans
(1)
,
Tregaye Lacey
(1)
,
Andrew Dearlove
(1)
,
John Greystrong
(1)
,
Joanne Walker
(1)
,
Paula Watson
(1)
,
Paul Weston
(1)
,
Maria Kelly
(1)
,
Dilip Taylor
(1)
,
Keith Gibson
(1)
,
Chris Mundy
(1)
,
Franck Bourgade
(2)
,
Christophe Poirier
(2)
,
Dominique Simon
(2)
,
Ana Lucia Bueno Brunialti
(2)
,
Xavier Montagutelli
(2)
,
Jean-Louis Guénet
(2)
,
Andy Haynes
(3)
,
Steve D.M. Brown
(3)
Franck Bourgade
- Function : Author
- PersonId : 747197
- IdHAL : franck-bourgade
- ORCID : 0009-0004-5351-4491
Xavier Montagutelli
- Function : Author
- PersonId : 181628
- IdHAL : xavier-montagutelli
- ORCID : 0000-0002-9372-5398
- IdRef : 07466638X
Steve D.M. Brown
Connectez-vous pour contacter l'auteur
- Function : Correspondent author
- PersonId : 947192
Connectez-vous pour contacter l'auteur
Abstract
The European Collaborative Interspecific Backcross (EUCIB) resource was constructed for the purposes of high-resolution genetic mapping of the mouse genome (). The large Mus spretus/C57BL/6 backcross of 982 progeny has a genetic resolution of 0.3 cM at the 95% confidence level ( approximately 500 kb in the mouse genome). We have used the EUCIB mapping resource to develop a genome-wide high-resolution genetic map incorporating 3368 microsatellites. The microsatellites are distributed among 2302 genetically separated bins with 1.46 markers per bin on average. Average bin separation is 0.61 cM. This high-resolution genetic map will aid the construction of a robust physical map of the mouse genome.