Antibodies to the leucine-rich repeat region of internalin block entry of Listeria monocytogenes into cells expressing E-cadherin - Institut Pasteur Access content directly
Journal Articles Infection and Immunity Year : 1996

Antibodies to the leucine-rich repeat region of internalin block entry of Listeria monocytogenes into cells expressing E-cadherin

Abstract

Internalin, a surface protein essential for entry of Listeria monocytogenes EGD into epithelial cells, was used as an antigen to raise nine monoclonal antibodies. These monoclonal antibodies recognized seven distinct epitopes which were located in three different regions of the protein. Three of them inhibited internalinmediated entry and recognized the amino-terminal leucine-rich repeat region of the protein, suggesting that this region is essential for entry.

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pasteur-03206290 , version 1 (23-04-2021)

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Jerome Mengaud, Marc Lecuit, Maryse Lebrun, Farida Nato, Jean-Claude Mazie, et al.. Antibodies to the leucine-rich repeat region of internalin block entry of Listeria monocytogenes into cells expressing E-cadherin. Infection and Immunity, 1996, 64 (12), pp.5430-5433. ⟨10.1128/IAI.64.12.5430-5433.1996⟩. ⟨pasteur-03206290⟩

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