Evolution of abiotic cubane chemistries in a nucleic acid aptamer allows selective recognition of a malaria biomarker - Institut Pasteur Access content directly
Journal Articles Proceedings of the National Academy of Sciences of the United States of America Year : 2020

Evolution of abiotic cubane chemistries in a nucleic acid aptamer allows selective recognition of a malaria biomarker

Julian A Tanner
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Abstract

for the overall study design and data interpretation. Y.W.C. performed all cubamer selections, characterized the cubamers and oversaw all application experiments. A.W.C.W., Y.L., and A.B.K. were involved in aspects of cubamer characterization and in assay design. F.L.-A. expressed and purified the proteins and performed the biochemical characterization of the triphosphate. P.R. performed all chemical syntheses and was involved in aspects of experimental design of cubamer structural analysis. P.R. was also significantly involved in all data interpretation. G.P.S. was involved in steps of synthesis relating to cubanes and advised on study design.
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Dates and versions

pasteur-03138380 , version 1 (11-02-2021)

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Attribution - NonCommercial

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Yee-Wai Cheung, Pascal Röthlisberger, Ariel E Mechaly, Patrick Weber, Fabienne Levi-Acobas, et al.. Evolution of abiotic cubane chemistries in a nucleic acid aptamer allows selective recognition of a malaria biomarker. Proceedings of the National Academy of Sciences of the United States of America, 2020, 117 (29), pp.16790-16798. ⟨10.1073/pnas.2003267117⟩. ⟨pasteur-03138380⟩
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