Assay for Hepatitis B Core-related Antigen Identify Patients With High Viral Load: Systematic Review and Meta-analysis of Individual Participant Data - Institut Pasteur Access content directly
Journal Articles Clinical Gastroenterology and Hepatology Year : 2020

Assay for Hepatitis B Core-related Antigen Identify Patients With High Viral Load: Systematic Review and Meta-analysis of Individual Participant Data

Sang Hoon Ahn
  • Function : Author
Maurizia Brunetto
  • Function : Author
  • PersonId : 880506
Masao Honda
  • Function : Author
Takeshi Matsui
  • Function : Author
Hidenori Toyoda
  • Function : Author
Bo Wang
Lai Wei
Hwai-I Yang
  • Function : Author
Yoshihiko Yano
  • Function : Author
Hiroshi Yatsuhashi
  • Function : Author
Maud Lemoine

Abstract

Scale-up of tests and treatments is needed to eliminate hepatitis B virus (HBV) infection from resource-limited countries. However, access to nucleic acid tests that quantify HBV DNA, to determine treatment eligibility, is severely limited. We performed a systematic review and meta-analysis to assess the performance of the hepatitis B core-related antigen (HBcrAg) immunoassay, a low-cost (less than $15/assay) alternative to the nucleic acid test, to identify highly viremic patients, infected with any HBV genotype.
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pasteur-02875203 , version 1 (16-12-2022)

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Attribution - NonCommercial

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Kyoko Yoshida, Alice Desbiolles, Sarah Feldman, Sang Hoon Ahn, Enagnon Alidjinou, et al.. Assay for Hepatitis B Core-related Antigen Identify Patients With High Viral Load: Systematic Review and Meta-analysis of Individual Participant Data. Clinical Gastroenterology and Hepatology, 2020, ⟨10.1016/j.cgh.2020.04.045⟩. ⟨pasteur-02875203⟩

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