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Generation and Analysis of Chromosomal Contact Maps of Bacteria

Abstract

This methods article described a protocol aiming at generating chromosome contact maps of bacterial species using a genome-wide derivative of the chromosome conformation capture (3C) technique. The approach is readily applicable on a broad variety of gram + and gram-bacterial species. It describes and addresses known caveats and technicalities associated with the technique, and should be of interest to any laboratory interested to perform a multiscale analysis of the genome structure of its species of interest.
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pasteur-02866638 , version 1 (12-06-2020)

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Martial Marbouty, Romain Koszul. Generation and Analysis of Chromosomal Contact Maps of Bacteria. Generation and Analysis of Chromosomal Contact Maps of Bacteria, 1624, pp.75-84, 2017, Methods in Molecular Biology, ⟨10.1007/978-1-4939-7098-8_7⟩. ⟨pasteur-02866638⟩
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