Of Insects and Viruses: The Role of Small RNAs in Insect Defence - Institut Pasteur Access content directly
Book Sections Year : 2012

Of Insects and Viruses: The Role of Small RNAs in Insect Defence

Nicolas Vodovar
Maria-Carla P Saleh

Abstract

In the past decade, small RNA pathways have been identified as a major mechanism of gene regulation. From an immunity standpoint, these pathways play a central role either by regulating immune reactions or by acting as immune effectors. In insects, several studies have unravelled the role of RNA interference (RNAi) as an antiviral response and have uncovered a complex relationship between insects and viruses that co-evolve in an ongoing race for supremacy. In this review, we comment on the role of small RNA pathways in insect defence and the exploitation of these same pathways by pathogens. We illustrate the host–pathogen relationship under RNAi constraints using several examples and we discuss future directions in using RNAi as a tool to control insect immunity.
Fichier principal
Vignette du fichier
vodovar_saleh_ms_final.pdf (3.29 Mo) Télécharger le fichier
Origin : Files produced by the author(s)
Loading...

Dates and versions

pasteur-02089877 , version 1 (15-04-2019)

Licence

Attribution - NonCommercial - ShareAlike

Identifiers

Cite

Nicolas Vodovar, Maria-Carla P Saleh. Of Insects and Viruses: The Role of Small RNAs in Insect Defence. Advances in Insect Physiology, 42, Elsevier, pp.1-36, 2012, 978-0-12-387680-5. ⟨10.1016/B978-0-12-387680-5.00001-X⟩. ⟨pasteur-02089877⟩

Collections

PASTEUR CNRS ANR
48 View
210 Download

Altmetric

Share

Gmail Facebook X LinkedIn More