Human candidate gene polymorphisms and risk of severe malaria in children in Kilifi, Kenya: a case-control association study - Institut Pasteur Access content directly
Journal Articles The Lancet Haematology Year : 2018

Human candidate gene polymorphisms and risk of severe malaria in children in Kilifi, Kenya: a case-control association study

Kevin Marsh
  • Function : Author
Margaret Mackinnon
  • Function : Author
Kathryn Maitland
  • Function : Author
Malariagen Consortium
  • Function : Author

Abstract

Background Human genetic factors are important determinants of malaria risk. We investigated associations between multiple candidate polymorphisms-many related to the structure or function of red blood cells-and risk for severe Plasmodium falciparum malaria and its specific phenotypes, including cerebral malaria, severe malaria anaemia, and respiratory distress.
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pasteur-02084676 , version 1 (29-03-2019)

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Carolyne M Ndila, Sophie Uyoga, Alexander W Macharia, Gideon Nyutu, Norbert Peshu, et al.. Human candidate gene polymorphisms and risk of severe malaria in children in Kilifi, Kenya: a case-control association study. The Lancet Haematology, 2018, 5 (8), pp.e333-e345. ⟨10.1016/S2352-3026(18)30107-8⟩. ⟨pasteur-02084676⟩

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