Host genetic control of mosquito-borne Flavivirus infections - Institut Pasteur Access content directly
Journal Articles Mammalian Genome Year : 2018

Host genetic control of mosquito-borne Flavivirus infections

Abstract

Flaviviruses are arthropod-borne viruses, several of which represent emerging or re-emerging pathogens responsible for widespread infections with consequences ranging from asymptomatic seroconversion to severe clinical diseases and congenital developmental deficits. This variability is due to multiple factors including host genetic determinants, the role of which has been investigated in mouse models and human genetic studies. In this review, we provide an overview of the host genes and variants which modify susceptibility or resistance to major mosquito-borne flaviviruses infections in mice and humans.
Fichier principal
Vignette du fichier
Manet et al. 2018 Host genetic control of Flavivirus infections.pdf (2.35 Mo) Télécharger le fichier
Origin : Files produced by the author(s)
Loading...

Dates and versions

pasteur-02003816 , version 1 (17-04-2019)

Licence

Attribution - NonCommercial - ShareAlike

Identifiers

Cite

Caroline Manet, Claude Roth, Ahmed Tawfik, Tineke Cantaert, Anavaj Sakuntabhai, et al.. Host genetic control of mosquito-borne Flavivirus infections. Mammalian Genome, 2018, 29 (7-8), pp.384-407. ⟨10.1007/s00335-018-9775-2⟩. ⟨pasteur-02003816⟩
237 View
495 Download

Altmetric

Share

Gmail Facebook X LinkedIn More