Toxin Detection in Patients' Sera by Mass Spectrometry during Two Outbreaks of Type A Botulism in France - Institut Pasteur Access content directly
Journal Articles Journal of Clinical Microbiology Year : 2012

Toxin Detection in Patients' Sera by Mass Spectrometry during Two Outbreaks of Type A Botulism in France

Abstract

In two outbreaks of food-borne botulism in France, Clostridium botulinum type A was isolated and characterized from incriminated foods. Botulinum neurotoxin type A was detected in the patients' sera by mouse bioassay and in vitro endopeptidase assay with an immunocapture step and identification of the cleavage products by mass spectrometry.

Dates and versions

pasteur-01762967 , version 1 (10-04-2018)

Identifiers

Cite

Christelle Mazuet, Eric Ezan, Hervé Volland, Michel Robert Popoff, François Becher. Toxin Detection in Patients' Sera by Mass Spectrometry during Two Outbreaks of Type A Botulism in France. Journal of Clinical Microbiology, 2012, 50 (12), pp.4091 - 4094. ⟨10.1128/JCM.02392-12⟩. ⟨pasteur-01762967⟩

Collections

PASTEUR CEA
103 View
0 Download

Altmetric

Share

Gmail Facebook X LinkedIn More