Bioluminescent fungi for real-time monitoring of fungal infections. - Institut Pasteur Access content directly
Journal Articles Virulence Year : 2010

Bioluminescent fungi for real-time monitoring of fungal infections.

Abstract

Novel luciferase reporters have been developed that allow real-time monitoring of infections by the fungal pathogens Candida albicans and Aspergillus fumigatus. Although these reporters still suffer limitations in the context of invasive infections, they provide unprecedented tools to monitor superficial infections and the efficacy of antifungal drugs or vaccines. In particular, the sensitivity and ease of detection of the cell-surface Gaussia princeps luciferase developed for C. albicans should make it a powerful tool for functional genomics studies in this and other pathogenic fungi.

Domains

Mycology
Fichier principal
Vignette du fichier
Bioluminescent fungi for real time monitoring of fungal infections.pdf (442.54 Ko) Télécharger le fichier
Origin : Publication funded by an institution
Loading...

Dates and versions

pasteur-01524679 , version 1 (18-05-2017)

Licence

Attribution - NonCommercial - NoDerivatives

Identifiers

Cite

Christophe D'Enfert, Anna Vecchiarelli, Alistair J P Brown. Bioluminescent fungi for real-time monitoring of fungal infections.. Virulence, 2010, 1 (3), pp.174-6. ⟨10.4161/viru.1.3.11119⟩. ⟨pasteur-01524679⟩

Collections

PASTEUR INRA INRAE
275 View
346 Download

Altmetric

Share

Gmail Facebook X LinkedIn More