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Journal Articles Angewandte Chemie International Edition Year : 2013

Sugar-Modified Foldamers as Conformationally Defined and Biologically Distinct Glycopeptide Mimics

Abstract

To fold or not to fold? It is shown that attached sugars play a defining role in the conformations adopted by a pair of novel SAA-derived foldamers in water and that these differences are reflected in the contrasting interactions of these glycofoldamers with various biological targets. C green, O red, N blue, H gray; yellow oval=mannose.

Dates and versions

pasteur-01385432 , version 1 (21-10-2016)

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Aloysius Siriwardena, Kiran Kumar Pulukuri, Pancham S. Kandiyal, Saumya Roy, Omprakash Bande, et al.. Sugar-Modified Foldamers as Conformationally Defined and Biologically Distinct Glycopeptide Mimics. Angewandte Chemie International Edition, 2013, 52 (39), pp.10221 - 10226. ⟨10.1002/anie.201304239⟩. ⟨pasteur-01385432⟩
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