Humanized mice: Current states and perspectives. - Institut Pasteur Access content directly
Journal Articles Immunology Letters Year : 2012

Humanized mice: Current states and perspectives.

Abstract

The development of chimeric mice bearing the components of a human immune system to serve as animal models for "human" diseases has been the goal of many years of research. In this review we will discuss the latest advances in this field, their remaining shortcomings and challenges to the generation of new models of mouse/human chimeras.

Domains

Immunology

Dates and versions

pasteur-00723372 , version 1 (09-08-2012)

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Sylvie Garcia, Antonio A Freitas. Humanized mice: Current states and perspectives.. Immunology Letters, 2012, 146 (1-2), pp.1-7. ⟨10.1016/j.imlet.2012.03.009⟩. ⟨pasteur-00723372⟩
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