RNA Dynamics from Experimental and Computational Approaches
Résumé
Ribonucleic acids (RNA) are unique in that they can store genetic information, replicate and
perform catalysis. Importantly, RNA molecules are highly dynamic, and thus determining the
ensemble of conformations that they populate is crucial not only to elucidate their biological
functions, but also for their potential use as therapeutic targets. Computational and experimental
techniques provide complementary views on RNA dynamics, and their integration is
fundamental to improve the accuracy of computations and the resolution of experiments. Recent
exciting developments in this field, were discussed at the CECAM workshop “RNA dynamics
from experimental and computational approaches”, in Paris, June 26-28, 2023. This report
outlines key ‘take-home’ messages that emerged during this workshop from the presentations
and discussions.
Domaines
Biologie structurale [q-bio.BM]Origine | Fichiers produits par l'(les) auteur(s) |
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Licence |
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