Higher convergence of human-great ape enteric eukaryotic viromes in central African forest than in a European zoo: A One Health analysis - Institut Pasteur Accéder directement au contenu
Article Dans Une Revue Nature Communications Année : 2023

Higher convergence of human-great ape enteric eukaryotic viromes in central African forest than in a European zoo: A One Health analysis

Résumé

Human-animal pathogenic transmissions threaten both human and animal health, and the processes catalyzing zoonotic spillover and spillback are complex. Prior field studies offer partial insight into these processes but overlook animal ecologies and human perceptions and practices facilitating human-animal contact. Conducted in Cameroon and a European zoo, this integrative study elucidates these processes, incorporating metagenomic, historical, anthropological and great ape ecological analyses, and real-time evaluation of human-great ape contact types and frequencies. We find more enteric eukaryotic virome sharing between Cameroonian humans and great apes than in the zoo, virome convergence between Cameroonian humans and gorillas, and adenovirus and enterovirus taxa as most frequently shared between Cameroonian humans and great apes. Together with physical contact from hunting, meat handling and fecal exposure, overlapping human cultivation and gorilla pillaging in forest gardens help explain these findings. Our multidisciplinary study identifies environmental co-use as a complementary mechanism for viral sharing.
Fichier principal
Vignette du fichier
s41467-023-39455-9.pdf (1.54 Mo) Télécharger le fichier
Origine : Publication financée par une institution
Licence : CC BY - Paternité

Dates et versions

pasteur-04122888 , version 1 (09-06-2023)

Licence

Paternité

Identifiants

Citer

Victor Narat, Maud Salmona, Mamadou Kampo, Thibaut Heyer, Abdeljalil Senhaji Rachik, et al.. Higher convergence of human-great ape enteric eukaryotic viromes in central African forest than in a European zoo: A One Health analysis. Nature Communications, 2023, 14 (1), pp.3674. ⟨10.1038/s41467-023-39455-9⟩. ⟨pasteur-04122888⟩
37 Consultations
38 Téléchargements

Altmetric

Partager

Gmail Facebook X LinkedIn More