Control of progression towards liver fibrosis and hepatocellular carcinoma by SOCS3 polymorphisms in chronic HCV-infected patients - Institut Pasteur Access content directly
Journal Articles Infection, Genetics and Evolution Year : 2018

Control of progression towards liver fibrosis and hepatocellular carcinoma by SOCS3 polymorphisms in chronic HCV-infected patients

Abstract

Chronic Hepatitis C is one of the most important risk factors of liver cirrhosis and hepatocellular carcinoma. Before reaching these ultimate steps, insulin resistance triggered by hepatitis C virus infection is known to participate in the progression of liver disease. The present study aims to investigate the influence of two functional polymorphisms on SOCS3 mRNA expression and on the outcomes of CHC progression in a North African context.

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Cancer
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pasteur-02611922 , version 1 (18-05-2020)

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Fatima Zahra Jadid, Hajar Chihab, Hanane Salih Alj, Raouia Elfihry, Imane Zaidane, et al.. Control of progression towards liver fibrosis and hepatocellular carcinoma by SOCS3 polymorphisms in chronic HCV-infected patients. Infection, Genetics and Evolution, 2018, 66, pp.1-8. ⟨10.1016/j.meegid.2018.08.027⟩. ⟨pasteur-02611922⟩
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