SME-4-producing Serratia marcescens from Argentina belonging to clade 2 of the S. marcescens phylogeny
Résumé
Background: SME carbapenemases are increasingly reported, especially from North and South America. Here, we describe an SME-4-producing Serratia marcescens (SME-Sm) clinical isolate from Argentina and compare its genome with other SME-Sm and Sm isolates recovered from public databases. Methods: Sm isolates were characterized by WGS using Illumina technology, susceptibility testing and MIC determination. Carbapenemase activity was revealed by biochemical tests based on imipenem hydrolysis. A whole-genome phylogeny was estimated for all the Sm isolates retrieved from public databases with kSNP3 and a whole-genome phylogenetic analysis based on non-recombinant core SNPs was inferred for Sm complete genomes and for those encoding any bla SME variants.
Domaines
Biologie moléculaire
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Dabos_et_al_revised_SME.pdf (2.26 Mo)
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Dabos_et_al_Supp_SME.pdf (2.88 Mo)
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