Revised nomenclature of Clostridium difficile toxins and associated genes
Maja Rupnik
(1)
,
Bruno Dupuy
(2)
,
Neil Fairweather
(3)
,
Dale N Gerding
(4, 5)
,
Stuart Johnson
(4, 5)
,
Ingo Just
(6)
,
David M Lyerly
(7)
,
Michel Robert Popoff
(8)
,
Julian I. Rood
(9)
,
Abraham L Sonenshein
(10)
,
Monica Thelestam
(11)
,
Brendan W Wren
(12)
,
Tracy D Wilkins
(7)
,
Christoph von Eichel-Streiber
(13)
1
University of Ljubljana
2 Génétique Moléculaire Bactérienne
3 CMBI - MRC Centre for Molecular Microbiology and Infection [Imperial College, London]
4 Hines VA Medical Center [USA]
5 LUMC - Loyola University Medical Center
6 Institut für Toxikologie - Institut for Toxicology [Hannover, Germany]
7 TechLab Inc
8 Toxines bactériennes - Bacterial Toxins
9 Department of Microbiology [Monash University, Australia]
10 Department of Molecular Biology and Microbiology [Tufts, Boston]
11 Department of Microbiology Tumor and Cell Biology [Stockholm]
12 LSHTM - London School of Hygiene and Tropical Medicine
13 JGU - Johannes Gutenberg - Universität Mainz = Johannes Gutenberg University
2 Génétique Moléculaire Bactérienne
3 CMBI - MRC Centre for Molecular Microbiology and Infection [Imperial College, London]
4 Hines VA Medical Center [USA]
5 LUMC - Loyola University Medical Center
6 Institut für Toxikologie - Institut for Toxicology [Hannover, Germany]
7 TechLab Inc
8 Toxines bactériennes - Bacterial Toxins
9 Department of Microbiology [Monash University, Australia]
10 Department of Molecular Biology and Microbiology [Tufts, Boston]
11 Department of Microbiology Tumor and Cell Biology [Stockholm]
12 LSHTM - London School of Hygiene and Tropical Medicine
13 JGU - Johannes Gutenberg - Universität Mainz = Johannes Gutenberg University
Maja Rupnik
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- Function : Correspondent author
- PersonId : 1063396
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Bruno Dupuy
- Function : Author
- PersonId : 746769
- IdHAL : bruno-dupuy
Michel Robert Popoff
- Function : Author
- PersonId : 16850
- IdHAL : michel-popoff
- ORCID : 0000-0001-9305-8989
- IdRef : 085586560
Abstract
Several different nomenclatures have been applied to the Clostridium difficile toxins and their associated genes. This paper summarizes the new nomenclature that has been agreed to by the research groups currently active in the field. The revised nomenclature includes C. difficile toxins and other related large clostridial toxins produced by Clostridium sordellii and Clostridium novyi, and corresponding toxin genes, as well as toxin production types of C. difficile strains.