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New insights into human immunity from ancient genomics

Gaspard Kerner , Etienne Patin , Lluis Quintana-Murci
Current Opinion in Immunology, 2021, 72, pp.116-125. ⟨10.1016/j.coi.2021.04.006⟩
Journal articles hal-03372683v1
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The genetic and evolutionary determinants of COVID-19 susceptibility

Gaspard Kerner , Lluis Quintana-Murci
European Journal of Human Genetics, 2022, 30 (8), pp.915-921. ⟨10.1038/s41431-022-01141-7⟩
Journal articles pasteur-04005972v1
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The genomic signatures of natural selection in admixed human populations

Sebastian Cuadros-Espinoza , Guillaume Laval , Lluis Quintana-Murci , Etienne Patin
American Journal of Human Genetics, 2022, 109 (4), pp.710 - 726. ⟨10.1016/j.ajhg.2022.02.011⟩
Journal articles hal-03695997v2
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Innate immune pathways act synergistically to constrain RNA virus evolution in Drosophila melanogaster

Vanesa Mongelli , Sebastian Lequime , Athanasios Kousathanas , Valérie Gausson , Hervé Blanc , et al.
Nature Ecology & Evolution, 2022, ⟨10.1038/s41559-022-01697-z⟩
Journal articles pasteur-03602877v1

Genetic adaptation to pathogens and increased risk of inflammatory disorders in post-Neolithic Europe

Gaspard Kerner , Anna-Lena Neehus , Quentin Philippot , Jonathan Bohlen , Darawan Rinchai , et al.
Cell Genomics, 2023, 3 (2), pp.100248. ⟨10.1016/j.xgen.2022.100248⟩
Journal articles hal-04096029v1
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Paléogénomique et évolution du système immunitaire humain au cours des dix derniers millénaires

Gaspard Kerner , Lluís Quintana-Murci
Médecine/Sciences, 2023, 39 (6-7), pp.496-499. ⟨10.1051/medsci/2023070⟩
Journal articles hal-04147690v1

A global effort to dissect the human genetic basis of resistance to SARS-CoV-2 infection

Evangelos Andreakos , Laurent Abel , Donald Vinh , Elżbieta Kaja , Beth Drolet , et al.
Nature Immunology, 2022, 23 (2), pp.159-164. ⟨10.1038/s41590-021-01030-z⟩
Journal articles hal-03558195v1
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Sporadic Occurrence of Recent Selective Sweeps from Standing Variation in Humans as Revealed by an Approximate Bayesian Computation Approach

Guillaume Laval , Etienne Patin , Pierre Boutillier , Lluis Quintana-Murci
Genetics, 2021, 219 (4), ⟨10.1093/genetics/iyab161⟩
Journal articles pasteur-03560159v1
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Negative selection on human genes underlying inborn errors depends on disease outcome and both the mode and mechanism of inheritance

Franck Rapaport , Bertrand Boisson , Anne Gregor , Vivien Béziat , Stéphanie Boisson-Dupuis , et al.
Proceedings of the National Academy of Sciences of the United States of America, 2021, 118 (3), pp.e2001248118. ⟨10.1073/pnas.2001248118⟩
Journal articles hal-03372676v1
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Factors Driving DNA Methylation Variation in Human Blood

Jacob Bergstedt , Sadoune Ait Kaci Azzou , Kristin Tsuo , Anthony Jaquaniello , Alejandra Urrutia , et al.
Preprints, Working Papers, ... hal-03372695v1
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Biogeographic drivers of community assembly on oceanic islands: The importance of archipelago structure and history

Robin Aguilée , Félix Pellerin , Maxence Soubeyrand , Jeremy Choin , Christophe Thébaud
Journal of Biogeography, 2021, 48 (10), pp.2616 - 2628. ⟨10.1111/jbi.14228⟩
Journal articles hal-03378117v1

Diversity in immunogenomics: the value and the challenge

Kerui Peng , Yana Safonova , Mikhail Shugay , Alice B. Popejoy , Oscar L. Rodriguez , et al.
Nature Methods, 2021, ⟨10.1038/s41592-021-01169-5⟩
Journal articles pasteur-03236474v1
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High-throughput droplet-based analysis of influenza A virus genetic reassortment by single-virus RNA sequencing

Kuang-Yu Chen , Jayaprakash Karuppusamy , Mary O’neill , Vaitea Opuu , Mathieu Bahin , et al.
Proceedings of the National Academy of Sciences of the United States of America, 2023, 120 (6), pp.e2211098120. ⟨10.1073/pnas.2211098120⟩
Journal articles pasteur-04097895v1
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Genomic insights into population history and biological adaptation in Oceania

Jeremy Choin , Javier Mendoza-Revilla , Lara R Arauna , Sebastian Cuadros-Espinoza , Olivier Cassar , et al.
Nature, 2021, 592 (7855), pp.583-589. ⟨10.1038/s41586-021-03236-5⟩
Journal articles pasteur-03205291v1
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Single-Cell and Bulk RNA-Sequencing Reveal Differences in Monocyte Susceptibility to Influenza A Virus Infection Between Africans and Europeans

Mary B O’neill , Hélène Quach , Julien Pothlichet , Yann Aquino , Aurélie Bisiaux , et al.
Frontiers in Immunology, 2021, 12, ⟨10.3389/fimmu.2021.768189⟩
Journal articles hal-03499159v1
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Genomic perspectives on human dispersals during the Holocene

Mark Stoneking , Leonardo Arias , Dang Liu , Sandra Oliveira , Irina Pugach , et al.
Proceedings of the National Academy of Sciences of the United States of America, 2023, 120 (4), ⟨10.1073/pnas.2209475119⟩
Journal articles hal-03952281v1
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Integrated analysis of whole blood oxylipin and cytokine responses after bacterial, viral, and T cell stimulation reveals new immune networks

Etienne Villain , Aurélie Chanson , Malwina Mainka , Nadja Kampschulte , Pauline Le Faouder , et al.
iScience, 2023, 26 (8), pp.107422. ⟨10.1016/j.isci.2023.107422⟩
Journal articles pasteur-04186166v1
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The role of admixture in the adaptation of human populations to changing environments

Sebastian Cuadros Espinoza
Populations and Evolution [q-bio.PE]. Sorbonne Université, 2022. English. ⟨NNT : 2022SORUS043⟩
Theses tel-03715380v1

Une histoire génétique : notre diversité, notre évolution, notre adaptation

Lluis Quintana-Murci
Collège de France, 2021, 9782722605732. ⟨10.4000/books.cdf.11365⟩
Books hal-03888324v1
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Towards a functional understanding of adaptive phenotypes in humans.

Maxime Rotival , Lluis Quintana-Murci
JASs. Journal of anthropological sciences, 2021, 99, pp.171-174. ⟨10.4436/JASS.99006⟩
Journal articles hal-03594325v1
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Dissecting human population variation in single-cell responses to SARS-CoV-2

Yann Aquino , Aurélie Bisiaux , Zhi Li , Mary O'Neill , Javier Mendoza-Revilla , et al.
Nature, 2023, 53 (8), pp.e2250307. ⟨10.1038/s41586-023-06422-9⟩
Journal articles pasteur-04186119v1
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Human evolution: The unsealed fates of foragers and farmers

Etienne Patin
Current Biology - CB, 2022, 32 (8), pp.R362-R365. ⟨10.1016/j.cub.2022.03.015⟩
Journal articles hal-03811234v1
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The immune factors driving DNA methylation variation in human blood

Jacob Bergstedt , Sadoune Ait Kaci Azzou , Kristin Tsuo , Anthony Jaquaniello , Alejandra Urrutia , et al.
Nature Communications, 2022, 13 (1), pp.5895. ⟨10.1038/s41467-022-33511-6⟩
Journal articles pasteur-03865045v1
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Genetic origins, singularity, and heterogeneity of Basques

André Flores-Bello , Frédéric Bauduer , Jasone Salaberria , Bernard Beñat, B. Oyharçabal , Francesc Calafell , et al.
Current Biology - CB, 2021, ⟨10.1016/j.cub.2021.03.010⟩
Journal articles pasteur-03199264v1
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Early IFNβ secretion determines variable downstream IL-12p70 responses upon TLR4 activation

Celine Posseme , Alba Llibre , Bruno Charbit , Vincent Bondet , Vincent Rouilly , et al.
Cell Reports, 2022, 39 (13), pp.110989. ⟨10.1016/j.celrep.2022.110989⟩
Journal articles pasteur-03244390v2
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A loss-of-function IFNAR1 allele in Polynesia underlies severe viral diseases in homozygotes

Jean-Laurent Casanova , Andrew Wood , Lluis Quintana-Murci , Ryan Minster , Andrés Moreno-Estrada , et al.
Journal of Experimental Medicine, 2022, 219 (6), pp.e20220028. ⟨10.1084/jem.20220028⟩
Journal articles pasteur-03681917v1
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The genomic landscape of contemporary western Remote Oceanians

Lara R Arauna , Jacob Bergstedt , Jeremy Choin , Javier Mendoza-Revilla , Christine Harmant , et al.
Current Biology - CB, 2022, 32 (21), pp.4565 - 4575.e6. ⟨10.1016/j.cub.2022.08.055⟩
Journal articles hal-03885644v1
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Vaccine breakthrough hypoxemic COVID-19 pneumonia in patients with auto-Abs neutralizing type I IFNs

Paul Bastard , Sara Vazquez , Jamin Liu , Matthew T Laurie , Chung Yu Wang , et al.
Science Immunology, 2022, ⟨10.1126/sciimmunol.abp8966⟩
Journal articles hal-03948899v1
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Automatic landmarking identifies new loci associated with face morphology and implicates Neanderthal introgression in human nasal shape.

Qing Li , Jieyi Chen , Pierre Faux , Miguel Eduardo Delgado , Betty Bonfante , et al.
Communications Biology, 2023, 6 (1), pp.481. ⟨10.1038/s42003-023-04838-7⟩
Journal articles hal-04115851v1
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Environmental and genetic drivers of population differences in SARS-CoV-2 immune responses

Yann Aquino , Aurélie Bisiaux , Zhi Li , Mary O’neill , Javier Mendoza-Revilla , et al.
Preprints, Working Papers, ... pasteur-03913748v1