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Structure: Internal structure identifier : 1090787
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Parallel in vivo experimental evolution reveals that increased stress resistance was key for the emergence of persistent tuberculosis bacilli

Aideen C Allen , Wladimir Malaga , Cyril Gaudin , Arnaud Volle , Flavie Moreau , et al.
Nature Microbiology, 2021, 6 (8), pp.1082-1093. ⟨10.1038/s41564-021-00938-4⟩
Journal articles hal-03318178v1
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De novo synthesized polyunsaturated fatty acids operate as both host immunomodulators and nutrients for Mycobacterium tuberculosis

Thomas Laval , Laura Pedró-Cos , Wladimir Malaga , Laure Guenin-Macé , Alexandre Pawlik , et al.
eLife, 2021, 10, pp.e71946. ⟨10.7554/eLife.71946⟩
Journal articles pasteur-03534651v1
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The C terminus of the mycobacterium ESX-1 secretion system substrate ESAT-6 is required for phagosomal membrane damage and virulence

Morwan M. Osman , Jonathan K. Shanahan , Frances Chu , Kevin K. Takaki , Malte L. Pinckert , et al.
Proceedings of the National Academy of Sciences of the United States of America, 2022, 119 (11), pp.e2122161119. ⟨10.1073/pnas.2122161119⟩
Journal articles pasteur-03648366v1
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A lentiviral vector expressing a dendritic cell-targeting multimer induces mucosal anti-mycobacterial CD4+ T-cell immunity

François Anna , Jodie Lopez , Fanny Moncoq , Catherine Blanc , Pierre Authié , et al.
Mucosal Immunology, 2022, 15 (6), pp.1389-1404. ⟨10.1038/s41385-022-00566-z⟩
Journal articles pasteur-03909615v1
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The Mycobacterium tuberculosis PhoPR virulence system regulates expression of the universal second messenger c-di-AMP and impacts vaccine safety and efficacy

Irene Pérez , Elena Campos-Pardos , Caridad Díaz , Santiago Uranga , Fadel Sayes , et al.
Molecular Therapy - Nucleic Acids, 2022, 27, pp.1235-1248. ⟨10.1016/j.omtn.2022.02.011⟩
Journal articles pasteur-03648358v1
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Natural mutations in the sensor kinase of the PhoPR two-component regulatory system modulate virulence of ancestor-like tuberculosis bacilli

Wladimir Malaga , Delphine Payros , Eva Meunier , Wafa Frigui , Fadel Sayes , et al.
PLoS Pathogens, 2023, 19 (7), pp.e1011437. ⟨10.1371/journal.ppat.1011437⟩
Journal articles hal-04163557v1
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Enhancing tuberculosis treatment with host-targeting strategies

Alexandra Maure
Human health and pathology. Université Paris Cité, 2021. English. ⟨NNT : 2021UNIP7331⟩
Theses tel-04106189v1
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A lentiviral vector encoding fusion of light invariant chain and mycobacterial antigens induces protective CD4+ T cell immunity

Jodie Lopez , François Anna , Pierre Authié , Alexandre Pawlik , Min-Wen Ku , et al.
Cell Reports, 2022, 40 (4), pp.111142. ⟨10.1016/j.celrep.2022.111142⟩
Journal articles pasteur-03909608v1