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authIdHal_s : sebastien-brier
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Characterization of a highly neutralizing single monoclonal antibody to botulinum neurotoxin type A

Sébastien Brier , Christine Rasetti-Escargueil , Anne Wijkhuisen , Stéphanie Simon , Maud Marechal , et al.
FASEB Journal, 2021, 35 (5), ⟨10.1096/fj.202002492R⟩
Journal articles pasteur-03254500v1

SEC-SAXS and HDX-MS: A powerful combination. The case of the calcium-binding domain of a bacterial toxin

Darragh O'Brien , Sebastien Brier , Daniel Ladant , Dominique Durand , Alexandre Chenal , et al.
Biotechnology and Applied Biochemistry, 2018, 65 (1), pp.62-68. ⟨10.1002/bab.1577⟩
Journal articles hal-02329435v1
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Calmodulin fishing with a structurally disordered bait triggers CyaA catalysis

Darragh P. O'Brien , Dominique Durand , Alexis Voegele , Véronique Hourdel , Marilyne Davi , et al.
PLoS Biology, 2017, 15 (12), pp.e2004486. ⟨10.1371/journal.pbio.2004486⟩
Journal articles hal-02294928v1
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Hydrogen/Deuterium Exchange Mass Spectrometry for the Structural Analysis of Detergent-Solubilized Membrane Proteins

Darragh O’brien , Véronique Hourdel , Alexandre Chenal , Sébastien Brier
Springer. Expression, Purification, and Structural Biology of Membrane Proteins, 2127, Humana, New York, NY, pp.339-358, 2020, Methods in Molecular Biology, 978-1-0716-0372-7. ⟨10.1007/978-1-0716-0373-4_22⟩
Book sections pasteur-02559306v1

Post-translational acylation controls the folding and functions of the CyaA RTX toxin

Darragh O'Brien , Sara E Cannella , Alexis Voegele , Dorothée Raoux-Barbot , Marilyne Davi , et al.
FASEB Journal, 2019, 33 (9), pp.10065-10076. ⟨10.1096/fj.201802442RR⟩
Journal articles pasteur-02330713v1
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A High‐Affinity Calmodulin‐Binding Site in the CyaA Toxin Translocation Domain is Essential for Invasion of Eukaryotic Cells

Alexis Voegele , Mirko Sadi , Darragh Patrick O'Brien , Pauline Gehan , Dorothée Raoux‐barbot , et al.
Advanced Science, 2021, pp.2003630. ⟨10.1002/advs.202003630⟩
Journal articles pasteur-03211832v1
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Post-translational acylation controls the folding and functions of the CyaA RTX toxin

Darragh P O'Brien , Sara E Cannella , Alexis Voegele , Dorothée Raoux-Barbot , Maryline Davi , et al.
Preprints, Working Papers, ... pasteur-03221015v1

Translocation and calmodulin-activation of the adenylate cyclase toxin (CyaA) of Bordetella pertussis

Alexis Voegele , Darragh P. O'Brien , Orso Subrini , Nicolas Sapay , Sara E. Cannella , et al.
Pathogens and Disease, 2018, 76 (8), pp.fty085. ⟨10.1093/femspd/fty085⟩
Journal articles hal-02184809v1

Calcium-dependent disorder-to-order transitions are central to the secretion and folding of the CyaA toxin of Bordetella pertussis, the causative agent of whooping cough

Darragh P. O'Brien , Ana Cristina Sotomayor Perez , Johanna Karst , Sara E. Cannella , Véronique Yvette Ntsogo Enguéné , et al.
Journal articles hal-02183106v1
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Structural models of intrinsically disordered and calcium-bound folded states of a protein adapted for secretion

Darragh P. O’brien , Belen Hernandez , Dominique Durand , Véronique Hourdel , Ana-Cristina Sotomayor-Pérez , et al.
Scientific Reports, 2016, 5, ⟨10.1038/srep14223⟩
Journal articles pasteur-01406897v1
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MEMHDX: An interactive tool to expedite the statistical validation and visualization of large HDX-MS datasets

Véronique Hourdel , Stevenn Volant , Darragh P. O'Brien , Alexandre Chenal , Julia Chamot-Rooke , et al.
Journal articles pasteur-01377055v1

Disorder-To-Order Transitions and Post-Translational Acylation Control the Folding and Activity of the Bordetella Pertussis CyaA Toxin

Darragh P. O'Brien , Alexis Voegele , Dorothee Raoux-Barbot , Marilyne Davi , Sara Cannella , et al.
Biophysical Journal, 2020, 118 (3), pp.197A--197A
Journal articles hal-02516165v1

Structural Characterization of Whirlin Reveals an Unexpected and Dynamic Supramodule Conformation of Its PDZ Tandem

Florent Delhommel , Florence Cordier , Benjamin Bardiaux , Guillaume Bouvier , Baptiste Colcombet-Cazenave , et al.
Structure, 2017, 25 (11), pp.1645-1656.e5. ⟨10.1016/j.str.2017.08.013⟩
Journal articles pasteur-02883914v1
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Development of a highly specific and sensitive VHH-based sandwich immunoassay for the detection of the SARS-CoV-2 nucleoprotein

Marion Gransagne , Gabriel Aymé , Sébastien Brier , Gaëlle Chauveau-Le Friec , Véronique Meriaux , et al.
Journal of Biological Chemistry, 2022, 298 (1), pp.101290. ⟨10.1016/j.jbc.2021.101290⟩
Journal articles pasteur-03524979v1
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Structure and allosteric inhibition of excitatory amino acid transporter 1

Juan C Canul-Tec , Reda Assal , Erica Cirri , Pierre Legrand , Sebastien Brier , et al.
Nature, 2017, 544 (7651), pp.446 - 451. ⟨10.1038/nature22064⟩
Journal articles hal-03053914v2
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Consensus designs and thermal stability determinants of a human glutamate transporter

Erica Cirri , Sébastien Brier , Reda Assal , Juan Carlos Canul-Tec , Julia Chamot-Rooke , et al.
Journal articles pasteur-01916344v1
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The stress sigma factor of RNA polymerase RpoS/σ S is a solvent-exposed open molecule in solution

Paola Cavaliere , Sebastien Brier , Petr Filipenko , Christina Sizun , Bertrand Raynal , et al.
Biochemical Journal, 2018, 475 (1), pp.341 - 354. ⟨10.1042/BCJ20170768⟩
Journal articles pasteur-01685123v1
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Dynamics of a type 2 secretion system pseudopilus unraveled by complementary approaches

Benjamin Bardiaux , Florence Cordier , Sébastien Brier , Aracelys López-Castilla , Nadia Izadi-Pruneyre , et al.
Journal of Biomolecular NMR, 2019, 73 (6-7), pp.293-303. ⟨10.1007/s10858-019-00246-4⟩
Journal articles hal-02990168v1
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Structural disorder and induced folding within two cereal, ABA stress and ripening (ASR) proteins

Karama Hamdi , Edoardo Salladini , Darragh O'Brien , Sebastien Brier , Alexandre Chenal , et al.
Scientific Reports, 2017, 7, pp.15544. ⟨10.1038/s41598-017-15299-4⟩
Journal articles hal-01802824v1
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Dynamics and structural changes of calmodulin upon interaction with the antagonist calmidazolium

Corentin Léger , Irène Pitard , Mirko Sadi , Nicolas Carvalho , Sébastien Brier , et al.
BMC Biology, 2022, 20 (1), pp.176. ⟨10.1186/s12915-022-01381-5⟩
Journal articles pasteur-03880614v1