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authIdHal_s : lguenin

Mycolactone suppresses T cell responsiveness by altering both early signaling and posttranslational events.

Sheerazed Boulkroun , Laure Guenin-Macé , Maria-Isabel Thoulouze , Marc Monot , Anaïs Merckx , et al.
Journal of Immunology, 2010, 184 (3), pp.1436-44. ⟨10.4049/jimmunol.0902854⟩
Journal articles pasteur-00594632v1
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Effect of gut microbiota on depressive-like behaviors in mice is mediated by the endocannabinoid system

Grégoire Chevalier , Eleni Siopi , Laure Guenin-Macé , Maud Pascal , Thomas Laval , et al.
Nature Communications, 2020, 11 (1), ⟨10.1038/s41467-020-19931-2⟩
Journal articles hal-03231388v1

Synthetic Variants of Mycolactone Bind and Activate Wiskott–Aldrich Syndrome Proteins

Anne-Caroline Chany , Romain Veyron-Churlet , Cédric Tresse , Véronique Mayau , Virginie Casarotto , et al.
Journal of Medicinal Chemistry, 2014, 57 (17), pp.7382 - 7395. ⟨10.1021/jm5008819⟩
Journal articles pasteur-03320888v1
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Spatiotemporal analysis of mycolactone distribution in vivo reveals partial diffusion in the central nervous system

Emma Colucci-Guyon , Aline Rifflet , Sarah Saint-Auret , Anaëlle da Costa , Laurent Boucontet , et al.
PLoS Neglected Tropical Diseases, 2020, 14 (12), pp.e0008878. ⟨10.1371/journal.pntd.0008878⟩
Journal articles pasteur-03046953v1
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Metabolomic profiles delineate mycolactone signature in Buruli ulcer disease

Fatoumata Niang , Fred S. Sarfo , Michael Frimpong , Laure Guenin-Macé , Mark Wansbrough-Jones , et al.
Scientific Reports, 2015, 5, pp.17693 - 17693. ⟨10.1038/srep17693⟩
Journal articles pasteur-01383808v1
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Molecular Mechanisms Underpinning the Circulation and Cellular Uptake of Mycobacterium ulcerans Toxin Mycolactone

Bruno Tello Rubio , Florence Bugault , Blandine Baudon , Bertrand Raynal , Sébastien Brûlé , et al.
Frontiers in Pharmacology, 2021, 12, pp.733496. ⟨10.3389/fphar.2021.733496⟩
Journal articles hal-03358263v1
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Mycolactone impairs T cell homing by suppressing microRNA control of L-selectin expression.

Laure Guenin-Macé , Florent Carrette , François Asperti-Boursin , Agnès Le Bon , Laxmee Caleechurn , et al.
Proceedings of the National Academy of Sciences of the United States of America, 2011, 108 (31), pp.12833-8. ⟨10.1073/pnas.1016496108⟩
Journal articles pasteur-00738806v1
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Immune-Epithelial Cross Talk in Regeneration and Repair

Laure Guenin-Mace , Piotr Konieczny , Shruti Naik
Annual Review of Immunology, 2023, 41 (1), pp.207-228. ⟨10.1146/annurev-immunol-101721-062818⟩
Journal articles pasteur-04098024v1

A Diverted Total Synthesis of Mycolactone Analogues: An Insight into Buruli Ulcer Toxins

Anne-Caroline Chany , Virginie Casarotto , Marjorie Schmitt , Céline Tarnus , Laure Guenin-Macé , et al.
Chemistry - A European Journal, 2011, 17 (51), pp.14413-14419. ⟨10.1002/chem.201102542⟩
Journal articles istex hal-02128753v1

Lipids of Pathogenic Mycobacteria: Contributions to Virulence and Host Immune Suppression

Laure Guenin-Macé , Roxane Simeone , Caroline Demangel
Transboundary and emerging diseases, 2009, 56 (6-7), pp.255-268. ⟨10.1111/j.1865-1682.2009.01072.x⟩
Journal articles istex pasteur-02863010v1
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De novo synthesized polyunsaturated fatty acids operate as both host immunomodulators and nutrients for Mycobacterium tuberculosis

Thomas Laval , Laura Pedró-Cos , Wladimir Malaga , Laure Guenin-Macé , Alexandre Pawlik , et al.
eLife, 2021, 10, pp.e71946. ⟨10.7554/eLife.71946⟩
Journal articles pasteur-03534651v1
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Mycolactone diffuses into the peripheral blood of Buruli ulcer patients--implications for diagnosis and disease monitoring.

Fred S. Sarfo , Fabien Le Chevalier , N'Guetta Aka , Richard O. Phillips , Yaw Amoako , et al.
PLoS Neglected Tropical Diseases, 2011, 5 (7), pp.e1237. ⟨10.1371/journal.pntd.0001237⟩
Journal articles inserm-00691438v1
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Shaping mycolactone for therapeutic use against inflammatory disorders

Laure Guenin-Mace , Ludivine Baron , Anne-Caroline Chany , Cédric Tresse , Sarah Saint-Auret , et al.
Science Translational Medicine, 2015, 7 (289), pp.289ra85 - 289ra85. ⟨10.1126/scitranslmed.aab0458⟩
Journal articles pasteur-01382767v1
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The impact of gut microbiota on depressive-like behaviors and adult hippocampal neurogenesis requires the endocannabinoid system

Grégoire Chevalier , Eleni Siopi , Laure Guenin-Macé , Maud Pascal , Thomas Laval , et al.
Preprints, Working Papers, ... pasteur-02873657v1
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Mycolactone Purification from M. ulcerans Cultures and HPLC-Based Approaches for Mycolactone Quantification in Biological Samples

Aline Rifflet , Caroline Demangel , Laure Guenin-Macé
Mycobacterium ulcerans, 2387, Springer US, pp.117-130, 2021, Methods in Molecular Biology, 978-1-0716-1779-3. ⟨10.1007/978-1-0716-1779-3_13⟩
Book sections pasteur-03534701v1

Immunosuppressive Signature of Cutaneous Mycobacterium ulcerans Infection in the Peripheral Blood of Patients with Buruli Ulcer Disease

Richard Phillips , Fred s. Sarfo , Laure Guenin‐macé , Jérémie Decalf , Mark Wansbrough‐jones , et al.
Journal of Infectious Diseases, 2009, 200 (11), pp.1675 - 1684. ⟨10.1086/646615⟩
Journal articles pasteur-01402286v1
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Pathogenesis of skin ulcers: lessons from the Mycobacterium ulcerans and Leishmania spp. pathogens

Laure Guenin-Macé , Reid Oldenburg , Fabrice Chrétien , Caroline Demangel
Cellular and Molecular Life Sciences, 2014, 71 (13), pp.2443 - 2450. ⟨10.1007/s00018-014-1561-z⟩
Journal articles pasteur-01387237v1
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Dysregulation of tryptophan catabolism at the host-skin microbiota interface in hidradenitis suppurativa

Laure Guenin-Macé , Jean-David Morel , Jean-Marc Doisne , Angèle Schiavo , Lysiane Boulet , et al.
JCI Insight, 2020, 5 (20), pp.e140598. ⟨10.1172/jci.insight.140598⟩
Journal articles pasteur-02983317v1
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Mycolactone subverts immunity by selectively blocking the Sec61 translocon.

Ludivine Baron , Anja Onerva Paatero , Jean-David Morel , Francis Impens , Laure Guenin-Macé , et al.
Journal of Experimental Medicine, 2016, 213 (13), pp.2885-2896. ⟨10.1084/jem.20160662⟩
Journal articles pasteur-01432024v1

Modular total syntheses of mycolactone A/B and its [ 2 H]- isotopologue

Sarah Saint-Auret , Hajer Abdelkafi , Didier Le Nouen , Laure Guenin-Macé , Caroline Demangel , et al.
Organic & Biomolecular Chemistry, 2017, 15, pp.7518-7522. ⟨10.1039/C7OB01943B⟩
Journal articles pasteur-01666631v1
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Mycolactone displays anti-inflammatory effects on the nervous system

Caroline Isaac , Annie Mauborgne , Alfonso Grimaldi , Kemy Ade , Michel Pohl , et al.
PLoS Neglected Tropical Diseases, 2017, 11 (11), pp.e0006058. ⟨10.1371/journal.pntd.0006058⟩
Journal articles pasteur-01664214v1
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Metabolic alterations in Hurley stage 1 Hidradenitis Suppurativa

Maïa Delage , Laure Guenin-Macé , Jean-David Morel , Jean-Marc Doisne , Angèle Schiavo , et al.
Conference poster hal-02911687v1
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Expression profiling of prospero in the Drosophila larval chemosensory organ: Between growth and outgrowth.

Laure Guenin , Mahatsangy Raharijaona , Rémi Houlgatte , Fawzia Baba-Aissa
BMC Genomics, 2010, 11 (1), pp.47. ⟨10.1186/1471-2164-11-47⟩
Journal articles inserm-00663539v1
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Mycolactone: More than Just a Cytotoxin

Laure Guenin‐macé , Marie-Thérèse Ruf , Gerd Pluschke , Caroline Demangel
Buruli Ulcer, Springer International Publishing, pp.117-134, 2019, 978-3-030-11114-4. ⟨10.1007/978-3-030-11114-4_7⟩
Book sections pasteur-03234888v1
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Mycolactone activation of Wiskott-Aldrich syndrome proteins underpins Buruli ulcer formation.

Laure Guenin-Macé , Romain Veyron-Churlet , Maria-Isabel Thoulouze , Guillaume Romet ‐ Lemonne , Hui Hong , et al.
Journal of Clinical Investigation, 2013, 123 (4), pp.1501-12. ⟨10.1172/JCI66576⟩
Journal articles pasteur-00874628v1
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Proteomics Reveals Scope of Mycolactone-mediated Sec61 Blockade and Distinctive Stress Signature

Jean-David Morel , Anja O Paatero , Jiajie Wei , Jonathan W. Yewdell , Laure Guenin-Macé , et al.
Molecular and Cellular Proteomics, 2018, 17 (9), pp.1750-1765. ⟨10.1074/mcp.RA118.000824⟩
Journal articles hal-02861787v1