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authIdHal_s : christophe-guilhot
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Pks5-recombination-mediated surface remodelling in Mycobacterium tuberculosis emergence

Eva C. Boritsch , Wafa Frigui , Alessandro Cascioferro , Wladimir Malaga , Gilles Etienne , et al.
Nature Microbiology, 2016, 1 (février 2016), ⟨10.1038/nmicrobiol.2015.19⟩
Journal articles pasteur-01265519v1

Efficient allelic exchange and transposon mutagenesis in Mycobacterium tuberculosis

V. Pelicic , Mary Jackson , Jean-Marc Reyrat , William R. Jacobs , Brigitte Gicquel , et al.
Proceedings of the National Academy of Sciences of the United States of America, 1997, 94 (20), pp.10955-10960. ⟨10.1073/pnas.94.20.10955⟩
Journal articles hal-03513941v1
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Parallel in vivo experimental evolution reveals that increased stress resistance was key for the emergence of persistent tuberculosis bacilli

Aideen C Allen , Wladimir Malaga , Cyril Gaudin , Arnaud Volle , Flavie Moreau , et al.
Nature Microbiology, 2021, 6 (8), pp.1082-1093. ⟨10.1038/s41564-021-00938-4⟩
Journal articles hal-03318178v1
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Mycobacterial Phenolic Glycolipids Selectively Disable TRIF-Dependent TLR4 Signaling in Macrophages

Reid Oldenburg , Véronique Mayau , Jacques Prandi , Ainhoa Arbues , Catherine Astarie-Dequeker , et al.
Frontiers in Immunology, 2018, 9, 12 p. ⟨10.3389/fimmu.2018.00002⟩
Journal articles hal-02323696v1

Mycobacterium leprae pgl1 expression by BCG increases CR3 mediated entry into mouse myeloid cells and induces Syk/NFAT cytokine production

Emilie Doz-Deblauwe , Florence Carreras , Aude Remot , Mathieu Epardaud , Caroline Demangel , et al.
Journées d'Animation Scientifique du Département Santé Animale, Oct 2018, Nantes, France. , 2018, Santé Animale et Santé Publique
Conference poster hal-02736584v1
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De novo synthesized polyunsaturated fatty acids operate as both host immunomodulators and nutrients for Mycobacterium tuberculosis

Thomas Laval , Laura Pedró-Cos , Wladimir Malaga , Laure Guenin-Macé , Alexandre Pawlik , et al.
eLife, 2021, 10, pp.e71946. ⟨10.7554/eLife.71946⟩
Journal articles pasteur-03534651v1
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Mycobacterium leprae Phenolglycolipid-1 Expressed by Engineered M. bovis BCG Modulates Early Interaction with Human Phagocytes

Guillaume Tabouret , Catherine Astarie-Dequeker , Caroline Demangel , Wladimir Malaga , Patricia Constant , et al.
PLoS Pathogens, 2010, 6 (10), pp.e1001159. ⟨10.1371/journal.ppat.1001159⟩
Journal articles pasteur-01376090v1

ESX-1 and phthiocerol dimycocerosates of Mycobacterium tuberculosis act in concert to cause phagosomal rupture and host cell apoptosis

Jacques Augenstreich , Ainhoa Arbues , Roxane Simeone , Evert Haanappel , Alice Wegener , et al.
Cellular Microbiology, 2017, 19 (7), pp.e12726. ⟨10.1111/cmi.12726⟩
Journal articles hal-02326055v1

Evolutionary history of tuberculosis shaped by conserved mutations in the PhoPR virulence regulator

J. Gonzalo-Asensio , W. Malaga , Alexandre Pawlik , Catherine Astarie-Dequeker , C. Passemar , et al.
Proceedings of the National Academy of Sciences of the United States of America, 2014, 111 (31), pp.11491-11496. ⟨10.1073/pnas.1406693111⟩
Journal articles hal-02325922v1

Bovine tubercle bacilli: evolution associated with loss of transmission capacity in humans

Roland Brosch , Christophe Guilhot
Médecine/Sciences, 2015, 31 (2), pp.123-126. ⟨10.1051/medsci/20153102003⟩
Journal articles hal-02325939v1

Phospholipases C are involved in the virulence of Mycobacterium tuberculosis

Catherine Raynaud , Christophe Guilhot , Jean Rauzier , Yann Bordat , V. Pelicic , et al.
Molecular Microbiology, 2002, 45 (1), pp.203-217. ⟨10.1046/j.1365-2958.2002.03009.x⟩
Journal articles hal-03514248v1

Identification of genetic loci implicated in the survival of Mycobacterium smegmatis in human mononuclear phagocytes

Béatrice Lagier , V. Pelicic , Denise Lecossier , Guy Prod'Hom , Jean Rauzier , et al.
Molecular Microbiology, 1998, 29 (2), pp.465-475. ⟨10.1046/j.1365-2958.1998.00933.x⟩
Journal articles hal-03513967v1
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CR3 engaged by PGL-I triggers Syk-calcineurin-NFATc to rewire the innate immune response in Leprosy.

Emilie Doz-Deblauwe , Florence Carreras , Ainhoa Arbues , Aude Remot , Mathieu Epardaud , et al.
Frontiers in Immunology, 2019, 10, 15 p. ⟨10.3389/fimmu.2019.02913⟩
Journal articles hal-02624164v1

From environmental bacteria to obligate human pathogen: adaptations associated with the emergence of tuberculosis bacilli

Delphine Payros , Wladimir Malaga , Alexandre Pawlik , Serge Mazères , Céline Berrone , et al.
EMBO Workshop. Pathogen immunity and signalling., Apr 2019, Oxford, United Kingdom
Conference papers hal-02341937v1
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Natural mutations in the sensor kinase of the PhoPR two-component regulatory system modulate virulence of ancestor-like tuberculosis bacilli

Wladimir Malaga , Delphine Payros , Eva Meunier , Wafa Frigui , Fadel Sayes , et al.
PLoS Pathogens, 2023, 19 (7), pp.e1011437. ⟨10.1371/journal.ppat.1011437⟩
Journal articles hal-04163557v1

Tn611 transposon mutagenesis in Mycobacterium smegmatis using a temperature-sensitive delivery system

Esther Pérez , Julie-Ann Gavigan , Isabel Otal , Christophe Guilhot , V. Pelicic , et al.
Mycobacteria Protocols, 101, Humana Press, pp.187-198, 1998, 978-1-59259-576-1. ⟨10.1385/0-89603-471-2:187⟩
Book sections hal-03513995v1
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Phthiocerol Dimycocerosates From Mycobacterium tuberculosis Increase the Membrane Activity of Bacterial Effectors and Host Receptors

Jacques Augenstreich , Evert Haanappel , Fadel Sayes , Roxane Simeone , Valerie Guillet , et al.
Frontiers in Cellular and Infection Microbiology, 2020, 10, pp.420. ⟨10.3389/fcimb.2020.00420⟩
Journal articles pasteur-02873531v1

Molecular dissection of the biosynthetic relationship between phthiocerol and phthiodiolone dimycocerosates and their critical role in the virulence and permeability of Mycobacterium tuberculosis

Roxane Simeone , Patricia Constant , Wladimir Malaga , Christophe Guilhot , Mamadou Daffé , et al.
FEBS Journal, 2007, 274 (8), pp.1957-1969. ⟨10.1111/j.1742-4658.2007.05740.x⟩
Journal articles pasteur-02862986v1