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Released Parasite-Derived Kinases as Novel Targets for Antiparasitic Therapies

Anne Silvestre , Sharvani Shrinivas Shintre , Najma Rachidi
Frontiers in Cellular and Infection Microbiology, 2022, 12, 12 p. ⟨10.3389/fcimb.2022.825458⟩
Journal articles hal-03681384v1
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Identification of the Host Substratome of Leishmania-Secreted Casein Kinase 1 Using a SILAC-Based Quantitative Mass Spectrometry Assay

Despina Smirlis , Florent Dingli , Valentin Sabatet , Aileen Roth , Uwe Knippschild , et al.
Frontiers in Cell and Developmental Biology, 2022, 9, pp.800098. ⟨10.3389/fcell.2021.800098⟩
Journal articles pasteur-03524218v1

The low complexity regions in the C-terminus are essential for the subcellular localisation of Leishmania casein kinase 1 but not for its activity

Daniel Martel , Stewart Pine , Katharina Bartsch , Joachim Clos , Gerald Späth , et al.
Preprints, Working Papers, ... pasteur-02874585v1
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From drug screening to target deconvolution: A target-based drug discovery pipeline using Leishmania casein kinase 1 isoform 2 to identify compounds with anti-leishmanial activity

Emilie Durieu , Eric Prina , Olivier Leclercq , Nassima Oumata , Nicolas Gaboriaud-Kolar , et al.
Antimicrobial Agents and Chemotherapy, 2016, ⟨10.1128/AAC.00021-16⟩
Journal articles hal-01299756v1
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Dangerous Duplicity: The Dual Functions of Casein Kinase 1 in Parasite Biology and Host Subversion

Najma Rachidi , Uwe Knippschild , Gerald F Späth
Frontiers in Cellular and Infection Microbiology, 2021, 11, pp.655700. ⟨10.3389/fcimb.2021.655700⟩
Journal articles pasteur-03402709v1

Pharmacological assessment defines Leishmania donovani casein kinase 1 as a drug target and reveals important functions in parasite viability and intracellular infection

Najma Rachidi , Jean François Taly , Emilie Durieu , Olivier Leclercq , Nathalie Aulner , et al.
Antimicrobial Agents and Chemotherapy, 2014, 58 (3), pp.1501-1515. ⟨10.1128/AAC.02022-13⟩
Journal articles pasteur-01433412v1
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Characterisation of Casein Kinase 1.1 in Leishmania donovani Using the CRISPR Cas9 Toolkit

Daniel Martel , Tom Beneke , Eva Gluenz , Gerald F Späth , Najma Rachidi
BioMed Research International , 2017, 2017, pp.4635605. ⟨10.1155/2017/4635605⟩
Journal articles pasteur-01974292v1