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Crystallographic studies of pharmacological sites in pentameric ligand-gated ion channels
Ludovic Sauguet
,
Azadeh Shahsavar
,
Marc Delarue
Journal articles
pasteur-02167404v1
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How cyanophage S-2L rejects adenine and incorporates 2-aminoadenine to saturate hydrogen bonding in its DNA
Dariusz Czernecki
,
Pierre Legrand
,
Mustafa Tekpinar
,
Sandrine Rosario
,
Pierre-Alexandre Kaminski
,
et al.
Journal articles
hal-03208082v1
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Genuine open form of the pentameric ligand-gated ion channel GLIC
Zaineb Fourati
,
Ludovic Sauguet
,
Marc Delarue
Journal articles
pasteur-02174633v1
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Conferring a template-dependent polymerase activity to terminal deoxynucleotidyltransferase by mutations in the Loop1 region
Félix Romain
,
Isabelle Barbosa
,
Jérôme Gouge
,
François Rougeon
,
Marc Delarue
Journal articles
pasteur-02174751v1
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Structure of the DP1-DP2 PolD complex bound with DNA and its implications for the evolutionary history of DNA and RNA polymerases
Pierre Raia
,
Marta Carroni
,
Etienne Henry
,
Gérard Pehau-Arnaudet
,
Sébastien Brûlé
,
et al.
Journal articles
pasteur-02057758v1
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Electrostatics, proton sensor, and networks governing the gating transition in GLIC, a proton-gated pentameric ion channel
Haidai Hu
,
Kenichi Ataka
,
Anaïs Menny
,
Zaineb Fourati
,
Ludovic Sauguet
,
et al.
Proceedings of the National Academy of Sciences of the United States of America, 2018, 115 (52), pp.E12172-E12181. ⟨10.1073/pnas.1813378116⟩
Journal articles
pasteur-02170327v1
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Crystal Structure of the Extracellular Domain of a Bacterial Ligand-Gated Ion Channel
Hugues Nury
,
Nicolas Bocquet
,
Chantal Le Poupon
,
Bertrand Raynal
,
Ahmed Haouz
,
et al.
Journal articles
pasteur-02174748v1
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Structural basis for a novel mechanism of DNA bridging and alignment in eukaryotic DSB DNA repair
Jérôme Gouge
,
Sandrine Rosario
,
Félix Romain
,
Frédéric Poitevin
,
Pierre Béguin
,
et al.
Journal articles
pasteur-02167413v1
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Conditioned Langevin Dynamics enables efficient sampling of transition paths
Marc Delarue
,
Patrice Koehl
,
Henri Orland
2016
Preprints, Working Papers, ...
cea-01708354v1
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Structural Basis for a New Templated Activity by Terminal Deoxynucleotidyl Transferase: Implications for V(D)J Recombination
Jerome Loc'H
,
Sandrine Rosario
,
Marc Delarue
Journal articles
pasteur-02174621v1
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Refinement of docked protein-ligand and protein-DNA structures using low frequency normal mode amplitude optimization
Erik Lindahl
,
Marc Delarue
Journal articles
pasteur-02175164v1
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Terminal deoxynucleotidyltransferase: the story of an untemplated DNA polymerase also capable of DNA bridging and templated synthesis across strands
Jérôme Loc’h
,
Marc Delarue
Journal articles
pasteur-03414957v1
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Molecular recognition of canonical and deaminated bases by P. abyssi family B DNA polymerase.
Jérôme Gouge
,
Céline Ralec
,
Ghislaine Henneke
,
Marc Delarue
Journal articles
istex
hal-00775878v1
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Numerical Encodings of Amino Acids in Multivariate Gaussian Modeling of Protein Multiple Sequence Alignments
Patrice Koehl
,
Henri Orland
,
Marc Delarue
Journal articles
pasteur-02170325v1
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Crystal structures of a pentameric ion channel gated by alkaline pH show a widely open pore and identify a cavity for modulation
Haidai Hu
,
Ákos Nemecz
,
Catherine van Renterghem
,
Zaineb Fourati
,
Ludovic Sauguet
,
et al.
Proceedings of the National Academy of Sciences of the United States of America, 2018, 115 (17), pp.E3959-E3968. ⟨10.1073/pnas.1717700115⟩
Journal articles
pasteur-02174579v1
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Structures of Intermediates along the Catalytic Cycle of Terminal Deoxynucleotidyltransferase: Dynamical Aspects of the Two-Metal Ion Mechanism
Jérôme Gouge
,
Sandrine Rosario
,
Félix Romain
,
Pierre Béguin
,
Marc Delarue
Journal articles
pasteur-02174639v1
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Enzymatic synthesis of random sequences of RNA and RNA analogues by DNA polymerase theta mutants for the generation of aptamer libraries
Irina Randrianjatovo-Gbalou
,
Sandrine Rosario
,
Odile Sismeiro
,
Hugo Varet
,
Rachel Legendre
,
et al.
Journal articles
pasteur-02170331v1
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Dealing with structural variability in molecular replacement and crystallographic refinement through normal-mode analysis
Marc Delarue
Journal articles
pasteur-02175141v1
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Allosteric and hyperekplexic mutant phenotypes investigated on an α1 glycine receptor transmembrane structure.
Gustavo Moraga-Cid
,
Ludovic Sauguet
,
Christèle Huon
,
Laurie Malherbe
,
Christine Girard-Blanc
,
et al.
Proceedings of the National Academy of Sciences of the United States of America, 2015, 112 (9), pp.2865-70. ⟨10.1073/pnas.1417864112⟩
Journal articles
hal-01230762v1
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Characterization of a triad of genes in cyanophage S-2L sufficient to replace adenine by 2-aminoadenine in bacterial DNA
Dariusz Czernecki
,
Frédéric Bonhomme
,
Pierre-Alexandre Kaminski
,
Marc Delarue
Journal articles
pasteur-03327945v1
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Structural Studies of HNA Substrate Specificity in Mutants of an Archaeal DNA Polymerase Obtained by Directed Evolution
Camille Samson
,
Pierre Legrand
,
Mustafa Tekpinar
,
Jef Rozenski
,
Mikhail Abramov
,
et al.
Journal articles
pasteur-03269775v1
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Fast and efficient purification of SARS-CoV-2 RNA dependent RNA polymerase complex expressed in Escherichia coli
Clément Madru
,
Ayten Dizkirici Tekpinar
,
Sandrine Rosario
,
Dariusz Czernecki
,
Sébastien Brûlé
,
et al.
Journal articles
hal-03213590v1
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Shared active site architecture between archaeal PolD and multi-subunit RNA polymerases revealed by X-ray crystallography
Ludovic Sauguet
,
Pierre Raia
,
Ghislaine Henneke
,
Marc Delarue
Journal articles
pasteur-01389383v1
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Structural basis for allosteric transitions of a multidomain pentameric ligand-gated ion channel
Haidai Hu
,
Rebecca J. Howard
,
Ugo Bastolla
,
Erik Lindahl
,
Marc Delarue
Proceedings of the National Academy of Sciences of the United States of America, 2020, 117 (24), pp.13437-13446. ⟨10.1073/pnas.1922701117⟩
Journal articles
pasteur-02905610v1
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