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Nicotine upregulates its own receptors through enhanced intracellular maturation.

Jérôme Sallette , Stéphanie Pons , Anne Devillers-Thiery , Martine Soudant , Lia Prado de Carvalho , et al.
Neuron, 2005, 46 (4), pp.595-607. ⟨10.1016/j.neuron.2005.03.029⟩
Journal articles pasteur-00162539v1
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Atomic structure and dynamics of pentameric ligand-gated ion channels: new insight from bacterial homologues

Pierre-Jean Corringer , Marc Baaden , Nicolas Bocquet , Marc Delarue , Virginie Dufresne , et al.
The Journal of Physiology, 2010, 588 (4), pp.565-572. ⟨10.1113/jphysiol.2009.183160⟩
Journal articles pasteur-02174745v1

Functional prokaryotic-eukaryotic chimera from the pentameric ligand-gated ion channel family

Guillaume Duret , Catherine van Renterghem , Yun Weng , Marie Prevost , Gustavo Moraga-Cid , et al.
Proceedings of the National Academy of Sciences of the United States of America, 2011, 108 (29), pp.12143-12148. ⟨10.1073/pnas.1104494108⟩
Journal articles pasteur-03260319v1

Structure and Pharmacology of Pentameric Receptor Channels: From Bacteria to Brain

Pierre-Jean Corringer , Frédéric Poitevin , Marie S. Prévost , Ludovic Sauguet , Marc Delarue , et al.
Structure, 2012, 20 (6), pp.941 - 956. ⟨10.1016/j.str.2012.05.003⟩
Journal articles pasteur-01721985v1

An extracellular protein microdomain controls up-regulation of neuronal nicotinic acetylcholine receptors by nicotine.

Jérôme Sallette , Sébastien Bohler , Pierre Benoit , Martine Soudant , Stéphanie Pons , et al.
Journal of Biological Chemistry, 2004, 279 (18), pp.18767-75. ⟨10.1074/jbc.M308260200⟩
Journal articles pasteur-00163483v1
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Structure atomique de deux anesthésiques généraux liés à leur cible principale

Hugues Nury , Marc Delarue , Pierre-Jean Corringer
Médecine/Sciences, 2011, 27 (12), pp.1056 - 1057. ⟨10.1051/medsci/20112712006⟩
Journal articles pasteur-01724759v1
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Fumarate as positive modulator of allosteric transitions in the pentameric ligand-gated ion channel GLIC: Requirement of an intact vestibular pocket.

Catherine van Renterghem , Ákos Nemecz , Sandrine Delarue-Cochin , Delphine Joseph , Pierre‐Jean Corringer
The Journal of Physiology, In press, ⟨10.1113/JP283765⟩
Journal articles pasteur-04093140v1

X-ray structures of general anaesthetics bound to a pentameric ligand-gated ion channel.

Hugues Nury , Catherine van Renterghem , Yun Weng , Alphonso Tran , Marc Baaden , et al.
Nature, 2011, 469 (7330), pp.428-31. ⟨10.1038/nature09647⟩
Journal articles istex hal-00645160v1
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Mutational analysis to explore long-range allosteric couplings involved in a pentameric channel receptor pre-activation and activation

Solène N. Lefebvre , Antoine Taly , Anaïs Menny , Karima Medjebeur , Pierre-Jean Corringer
eLife, 2021, 10, pp.e60682. ⟨10.7554/eLife.60682⟩
Journal articles hal-03369647v2
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Generation of nanobodies acting as silent and positive allosteric modulators of the α7 nicotinic acetylcholine receptor

Qimeng Li , Ákos Nemecz , Gabriel Aymé , Gabrielle Dejean de la Bâtie , Marie S Prevost , et al.
2023
Preprints, Working Papers, ... pasteur-04094165v1