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FLP/FRT-mediated conditional mutagenesis in pre-erythrocytic stages of Plasmodium berghei

Céline Lacroix , Donatella Giovannini , Audrey Combe , Daniel Bargieri , Stephan Späth , et al.
Nature Protocols, 2011, 6 (9), pp.1412-1428. ⟨10.1038/nprot.2011.363⟩
Journal articles hal-02378670v1
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3D structures of the Plasmodium vivax subtilisin-like drug target SUB1 reveal conformational changes to accommodate a substrate-derived α-ketoamide inhibitor

Mariano Martinez , Fernando A Batista , Manon Maurel , Anthony Bouillon , Laura Ortega Varga , et al.
Acta crystallographica Section D : Structural biology [1993-..], 2023, 79 (8), ⟨10.1107/s2059798323004710⟩
Journal articles pasteur-04158872v1
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Cytometric measurement of in vitro inhibition of Plasmodium falciparum field isolates by drugs: a new approach for re-invasion inhibition study.

Marie Louise Varela , Romy Razakandrainibe , Delphine Aldebert , Jean Christophe Barale , Ronan Jambou
Malaria Journal, 2014, 13 (1), pp.110. ⟨10.1186/1475-2875-13-110⟩
Journal articles pasteur-00971508v1

In vitro activity of ferroquine against artemisinin-based combination therapy (ACT)-resistant Plasmodium falciparum isolates from Cambodia

Mélissa Mairet-Khedim , Flore Nardella , Nimol Khim , Saorin Kim , Nimol Kloeung , et al.
Journal of Antimicrobial Chemotherapy, 2019, 74 (11), pp.3240-3244. ⟨10.1093/jac/dkz340⟩
Journal articles pasteur-02385376v1

Gene targeting demonstrates that the Plasmodium berghei subtilisin PbSUB2 is essential for red cell invasion and reveals spontaneous genetic recombination events.

Pierrick Uzureau , Jean-Christophe Barale , Chris J Janse , Andrew P Waters , Catherine Braun Breton
Cellular Microbiology, 2004, 6 (1), pp.65-78. ⟨10.1046/j.1462-5822.2003.00343.x⟩
Journal articles hal-00126406v1

Reduced Artemisinin Susceptibility of Plasmodium falciparum Ring Stages in Western Cambodia

Benoît Witkowski , Nimol Khim , Pheaktra Chim , Saorin Kim , Sopheakvatey Ke , et al.
Antimicrobial Agents and Chemotherapy, 2013, 57 (2), pp.914-923. ⟨10.1128/AAC.01868-12⟩
Journal articles hal-02378668v1
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Computational Design of Protein-Based Inhibitors of Plasmodium vivax Subtilisin-Like 1 Protease

Giacomo Bastianelli , Anthony Bouillon , Christophe Nguyen , Dung Le-Nguyen , Michael Nilges , et al.
PLoS ONE, 2014, 9 (10), ⟨10.1371/journal.pone.0109269⟩
Journal articles pasteur-01414431v1

Plasmodium falciparum subtilisin-like protease 2, a merozoite candidate for the merozoite surface protein 1-42 maturase.

J. C. Barale , T. Blisnick , H. Fujioka , Pedro Maria Alzari , M. Aikawa , et al.
Proceedings of the National Academy of Sciences of the United States of America, 1999, 96 (11), pp.6445-50. ⟨10.1073/pnas.96.11.6445⟩
Journal articles hal-00126410v1
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In Silico screening on the three-dimensional model of the Plasmodium vivax SUB1 protease leads to the validation of a novel anti-parasite compound.

Anthony Bouillon , David Giganti , Christophe Benedet , Olivier Gorgette , Stéphane Pêtres , et al.
Journal of Biological Chemistry, 2013, 288, pp.18561-73. ⟨10.1074/jbc.M113.456764⟩
Journal articles pasteur-01457905v1

A Key Role for Plasmodium Subtilisin-like SUB1 Protease in Egress of Malaria Parasites from Host Hepatocytes

Lina Tawk , Céline Lacroix , Pascale Gueirard , Robyn Kent , Olivier Gorgette , et al.
Journal of Biological Chemistry, 2013, 288 (46), pp.33336-33346. ⟨10.1074/jbc.M113.513234⟩
Journal articles hal-02378664v1

A novel Plasmodium-specific prodomain fold regulates the malaria drug target SUB1 subtilase

David Giganti , Anthony Bouillon , Lina Tawk , Fabienne Robert , Mariano Martinez , et al.
Nature Communications, 2014, 5 (1), ⟨10.1038/ncomms5833⟩
Journal articles hal-02378692v1

A small-molecule cell-based screen led to the identification of biphenylimidazoazines with highly potent and broad-spectrum anti-apicomplexan activity

Espérance Moine , Caroline Denevault-Sabourin , Françoise Debierre-Grockiego , Laurence Silpa , Olivier Gorgette , et al.
European Journal of Medicinal Chemistry, 2015, 89, pp.386-400. ⟨10.1016/j.ejmech.2014.10.057⟩
Journal articles hal-02378633v1

Screening and Evaluation of Inhibitors of Plasmodium falciparum Merozoite Egress and Invasion Using Cytometry

Anthony Bouillon , Olivier Gorgette , Odile Mercereau-Puijalon , Jean-Christophe Barale
Malaria Methods and Protocols, 923, pp.523-534, 2012, Methods in Molecular Biology, 978-1-62703-026-7. ⟨10.1007/978-1-62703-026-7_36⟩
Book sections hal-02378675v1

Centromeric Plasmids and Artificial Chromosomes: New Kids on the Plasmodium Transfection Block

Jean-Christophe Barale , Robert Ménard
Cell Host and Microbe, 2010, 7 (3), pp.181-183. ⟨10.1016/j.chom.2010.03.002⟩
Journal articles hal-02378682v1
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Computational Reverse-Engineering of a Spider-Venom Derived Peptide Active Against Plasmodium falciparum SUB1

Giacomo Bastianelli , Anthony Bouillon , Christophe Nguyen , Elodie Crublet , Stéphane Pêtres , et al.
PLoS ONE, 2011, 6 (7), pp.e21812. ⟨10.1371/journal.pone.0021812⟩
Journal articles hal-02378677v1

On the Knorr synthesis of 6-bromo-4-methylquinolin-2(1H)-one

Nicolas Wlodarczyk , Catherine Simenel , Muriel Delepierre , Jean-Christophe Barale , Yves Louis Janin
Synthesis: Journal of Synthetic Organic Chemistry, 2011, 6, pp.934-942. ⟨10.1055/s-0030-1258440⟩
Journal articles pasteur-00584423v1
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Whole Pichia pastoris Yeast Expressing Measles Virus Nucleoprotein as a Production and Delivery System to Multimerize Plasmodium Antigens

Daria Jacob , Claude Ruffié , Myriam Dubois , Chantal Combredet , Rogerio Amino , et al.
PLoS ONE, 2014, 9, pp.e86658. ⟨10.1371/journal.pone.0086658⟩
Journal articles hal-02378658v1