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HLA-B*14:02-Restricted Env-Specific CD8+ T-Cell Activity Has Highly Potent Antiviral Efficacy Associated with Immune Control of HIV Infection

Ellen M Leitman , Christian B Willberg , Ming-Han Tsai , Huabiao Chen , Søren Buus , et al.
Journal of Virology, 2017, 91 (22), pp.e00544-17. ⟨10.1128/JVI.00544-17⟩
Journal articles pasteur-02549962v1

A global effort to dissect the human genetic basis of resistance to SARS-CoV-2 infection

Evangelos Andreakos , Laurent Abel , Donald Vinh , Elżbieta Kaja , Beth Drolet , et al.
Nature Immunology, 2022, 23 (2), pp.159-164. ⟨10.1038/s41590-021-01030-z⟩
Journal articles hal-03558195v1
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Distinctive roles of age, sex, and genetics in shaping transcriptional variation of human immune responses to microbial challenges

Barbara Piasecka , Darragh Duffy , Alejandra Urrutia , Hélène Quach , Etienne Patin , et al.
Proceedings of the National Academy of Sciences of the United States of America, 2018, 115 (3), pp.E488 - E497. ⟨10.1073/pnas.1714765115⟩
Journal articles pasteur-01721850v1
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Natural variation in the parameters of innate immune cells is preferentially driven by genetic factors

Etienne Patin , Milena Hasan , Jacob Bergstedt , Vincent Rouilly , Valentina Libri , et al.
Nature Immunology, 2018, 19 (3), pp.302 - 314. ⟨10.1038/s41590-018-0049-7⟩
Journal articles pasteur-01768943v1

Blacklisting variants common in private cohorts but not in public databases optimizes human exome analysis

Patrick Maffucci , Benedetta Bigio , Franck Rapaport , Aurélie Cobat , Alessandro Borghesi , et al.
Proceedings of the National Academy of Sciences of the United States of America, 2019, 116 (3), pp.950-959. ⟨10.1073/pnas.1808403116⟩
Journal articles hal-03888351v1
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A highly virulent variant of HIV-1 circulating in the Netherlands

Chris Wymant , Daniela Bezemer , François Blanquart , Luca Ferretti , Astrid Gall , et al.
Science, 2022, 375 (6580), pp.540-545. ⟨10.1126/science.abk1688⟩
Journal articles hal-03835688v1
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Rhesus negative males have an enhanced IFNγ-mediated immune response to influenza A virus

Jamie A. Sugrue , Megan Smith , Celine Posseme , Bruno Charbit , Nollaig M. Bourke , et al.
Genes and Immunity, 2022, ⟨10.1038/s41435-022-00169-5⟩
Journal articles pasteur-03648209v1
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Human genetic variants and age are the strongest predictors of humoral immune responses to common pathogens and vaccines

Milieu Intérieur Consortium , Petar Scepanovic , Cécile Alanio , Christian Hammer , Flavia Hodel , et al.
Genome Medicine, 2018, 10 (1), pp.59. ⟨10.1186/s13073-018-0568-8⟩
Journal articles pasteur-01758699v1
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SARS-CoV-2–related MIS-C: A key to the viral and genetic causes of Kawasaki disease?

Vanessa Sancho-Shimizu , Petter Brodin , Aurélie Cobat , Catherine Biggs , Julie Toubiana , et al.
Journal of Experimental Medicine, 2021, 218 (6), ⟨10.1084/jem.20210446⟩
Journal articles hal-03549287v1
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Inborn errors of type I IFN immunity in patients with life-threatening COVID-19

Qian Zhang , Paul Bastard , Zhiyong Liu , Jérémie Le Pen , Marcela Moncada-Velez , et al.
Science, 2020, 370 (6515), pp.eabd4570. ⟨10.1126/science.abd4570⟩
Journal articles hal-02950982v1
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Autoantibodies neutralizing type I IFNs are present in ~4% of uninfected individuals over 70 years old and account for ~20% of COVID-19 deaths

Paul Bastard , Adrian Gervais , Tom Le Voyer , Jeremie Rosain , Quentin Philippot , et al.
Science Immunology, 2021, 6 (62), pp.eabl4340. ⟨10.1126/sciimmunol.abl4340⟩
Journal articles hal-03358792v1
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The risk of COVID-19 death is much greater and age dependent with type I IFN autoantibodies

Jérémy Manry , Paul Bastard , Adrian Gervais , Tom Le Voyer , Jérémie Rosain , et al.
Proceedings of the National Academy of Sciences of the United States of America, 2022, 119 (21), pp.349-363. ⟨10.1073/pnas.2200413119⟩
Journal articles hal-03856619v2