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Reclassification of family A DNA polymerases reveals novel functional subfamilies and distinctive structural features

Dariusz Czernecki , Antonin Nourisson , Pierre Legrand , Marc Delarue
Nucleic Acids Research, 2023, 51 (9), pp.4488-4507. ⟨10.1093/nar/gkad242⟩
Journal articles pasteur-04112612v1
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How cyanophage S-2L rejects adenine and incorporates 2-aminoadenine to saturate hydrogen bonding in its DNA

Dariusz Czernecki , Pierre Legrand , Mustafa Tekpinar , Sandrine Rosario , Pierre-Alexandre Kaminski , et al.
Nature Communications, 2021, 12 (1), pp.2420. ⟨10.1038/s41467-021-22626-x⟩
Journal articles hal-03208082v1
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Trypanosoma brucei RRP44: a versatile enzyme for processing structured and non-structured RNA substrates

Giovanna Cesaro , Heloisa Tramontin da Soler , Eloise Pavão Guerra-Slompo , Ahmed Haouz , Pierre Legrand , et al.
Nucleic Acids Research, 2023, 51 (1), pp.380-395. ⟨10.1093/nar/gkac1199⟩
Journal articles pasteur-03980368v1
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DNA-binding mechanism and evolution of replication protein A

Clément Madru , Markel Martínez-Carranza , Sébastien Laurent , Alessandra Alberti , Maelenn Chevreuil , et al.
Nature Communications, 2023, 14 (1), pp.2326. ⟨10.1038/s41467-023-38048-w⟩
Journal articles hal-04112308v1
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The thiolation of uridine 34 in tRNA, which controls protein translation, depends on a [4Fe-4S] cluster in the archaeum Methanococcus maripaludis

Ornella Bimai , Pierre Legrand , Jean-Luc Ravanat , Nadia Touati , Jingjing Zhou , et al.
Scientific Reports, 2023, 13 (1), pp.5351. ⟨10.1038/s41598-023-32423-9⟩
Journal articles hal-04193139v1
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FtsEX-independent control of RipA-mediated cell separation in Corynebacteriales

Quentin Gaday , Daniela Megrian , Giacomo Carloni , Mariano Martinez , Bohdana Sokolova , et al.
Proceedings of the National Academy of Sciences of the United States of America, 2022, 119 (50), pp.e2214599119. ⟨10.1073/pnas.2214599119⟩
Journal articles pasteur-03914065v1
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The ion‐coupling mechanism of human excitatory amino acid transporters

Juan C Canul-Tec , Anand Kumar , Jonathan Dhenin , Redda Assal , Pierre Legrand , et al.
EMBO Journal, 2022, 41 (1), pp.377-390. ⟨10.15252/embj.2021108341⟩
Journal articles pasteur-03795591v1
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Structural Studies of HNA Substrate Specificity in Mutants of an Archaeal DNA Polymerase Obtained by Directed Evolution

Camille Samson , Pierre Legrand , Mustafa Tekpinar , Jef Rozenski , Mikhail Abramov , et al.
Biomolecules, 2020, 10 (12), pp.1647. ⟨10.3390/biom10121647⟩
Journal articles pasteur-03269775v1
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Pentameric ligand-gated ion channel ELIC is activated by GABA and modulated by benzodiazepines

Radovan Spurny , Joachim Ramerstorfer , Kerry Price , Marijke Brams , Margot Ernst , et al.
Proceedings of the National Academy of Sciences of the United States of America, 2012, 109 (44), pp.E3028 - E3034. ⟨10.1073/pnas.1208208109⟩
Journal articles pasteur-01721946v1
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Evolutionary diversification of the HAP2 membrane insertion motifs to drive gamete fusion across eukaryotes

Juliette Fedry , Jennifer Forcina , Pierre Legrand , Gérard Péhau-Arnaudet , Ahmed Haouz , et al.
PLoS Biology, 2018, 16 (8), pp.e2006357. ⟨10.1371/journal.pbio.2006357⟩
Journal articles pasteur-03525356v1
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Species-Specific Functional Regions of the Green Alga Gamete Fusion Protein HAP2 Revealed by Structural Studies

Eduard Baquero , Juliette Fedry , Pierre Legrand , Thomas Krey , Felix A. Rey
Structure, 2019, 27 (1), pp.113 - 124.e4. ⟨10.1016/j.str.2018.09.014⟩
Journal articles hal-03486165v1

Crystal structure and functional mapping of human ASMT, the last enzyme of the melatonin synthesis pathway.

Hany Goubran Botros , Pierre Legrand , Cecile Pagan , Vincent Bondet , Patrick Weber , et al.
Journal of Pineal Research, 2013, 54 (1), pp.46-57. ⟨10.1111/j.1600-079X.2012.01020.x⟩
Journal articles istex pasteur-01580140v1
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Atomic structure of Lanreotide nanotubes revealed by cryo-EM

Laura Pieri , Fengbin Wang , Ana-Andreea Arteni , Matthijn Vos , Jean-Marie Winter , et al.
Proceedings of the National Academy of Sciences of the United States of America, 2022, 119 (4), pp.e2120346119. ⟨10.1073/pnas.2120346119⟩
Journal articles hal-03541906v1