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Natural amines inhibit activation of human plasmacytoid dendritic cells through CXCR4 engagement

Nikaïa Smith , Nicolas Pietrancosta , Sophia Davidson , Jacques Dutrieux , Lise Chauveau , et al.
Nature Communications, 2017, 8, pp.14253. ⟨10.1038/ncomms14253⟩
Journal articles hal-02075366v1
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Targeting the chemokine receptor CXCR4 with histamine analogue to reduce inflammation in juvenile arthritis: a proof of concept for COVID-19 therapeutic approach

Nassima Bekaddour , Nikaïa Smith , Benoit Beitz , Alba Llibre , Tom Dott , et al.
2021
Preprints, Working Papers, ... hal-03430524v1
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Immune checkpoint inhibitors increase T cell immunity during SARS-CoV-2 infection

Nader Yatim , Jeremy Boussier , Pauline Tetu , Nikaïa Smith , Timothée Bruel , et al.
Science Advances , 2021, 7 (34), pp.eabg4081. ⟨10.1126/sciadv.abg4081⟩
Journal articles pasteur-03334080v1
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SARS-CoV-2 infection damages airway motile cilia and impairs mucociliary clearance

Rémy Robinot , Mathieu Hubert , Guilherme Dias de Melo , Françoise Lazarini , Timothée Bruel , et al.
2021
Preprints, Working Papers, ... pasteur-03244406v1
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La réponse interféron

Ghizlane Maarifi , Nikaïa Smith , Sébastien Nisole
Médecine/Sciences, 2020, 36 (3), pp.206-209. ⟨10.1051/medsci/2020032⟩
Journal articles hal-02903959v1
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Release of infectious virus and cytokines in nasopharyngeal swabs from individuals infected with non-alpha or alpha SARS-CoV-2 variants: an observational retrospective study

Blandine Monel , Delphine Planas , Ludivine Grzelak , Nikaïa Smith , Nicolas Robillard , et al.
EBioMedicine, 2021, 73, pp.103637. ⟨10.1016/j.ebiom.2021.103637⟩
Journal articles hal-03408666v1
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Tuberculosis alters immune-metabolic pathways resulting in perturbed IL-1 responses

Alba Llibre , Nikaïa Smith , Vincent Rouilly , Munyaradzi Musvosvi , Elisa Nemes , et al.
Frontiers in Immunology, 2022, 13, ⟨10.3389/fimmu.2022.897193⟩
Journal articles pasteur-03244395v2

Type I interferon response and vascular alteration in chilblain‐like lesions during the COVID‐19 outbreak

L. Frumholtz , J.‐d. Bouaziz , M. Battistella , J. Hadjadj , R. Chocron , et al.
British Journal of Dermatology, 2021, 185 (6), pp.1176-1185. ⟨10.1111/bjd.20707⟩
Journal articles hal-03892796v1

A monocyte/dendritic cell molecular signature of SARS-CoV-2-related multisystem inflammatory syndrome in children with severe myocarditis

Camille de Cevins , Marine Luka , Nikaïa Smith , Sonia Meynier , Aude Magérus , et al.
Med, 2021, 2 (9), pp.1072-1092.e7. ⟨10.1016/j.medj.2021.08.002⟩
Journal articles hal-03590894v1
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SARS-CoV-2 infection induces the dedifferentiation of multiciliated cells and impairs mucociliary clearance

Rémy Robinot , Mathieu Hubert , Guilherme Dias de Melo , Françoise Lazarini , Timothée Bruel , et al.
Nature Communications, 2021, 12 (1), pp.4354. ⟨10.1038/s41467-021-24521-x⟩
Journal articles pasteur-03319522v1
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Distinct systemic and mucosal immune responses to SARS-CoV-2

Nikaïa Smith , Pedro Goncalves , Bruno Charbit , Ludivine Grzelak , Maxime Beretta , et al.
2021
Preprints, Working Papers, ... pasteur-03244398v1
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Decreased Type I Interferon Production by Plasmacytoid Dendritic Cells Contributes to Severe Dengue

Vinit Upasani , Carolina Scagnolari , Federica Frasca , Nikaïa Smith , Vincent Bondet , et al.
Frontiers in Immunology, 2020, 11, pp.605087. ⟨10.3389/fimmu.2020.605087⟩
Journal articles pasteur-03245784v1

Sex Differences in Plasmacytoid Dendritic Cell Levels of IRF5 Drive Higher IFN-α Production in Women.

Morgane Griesbeck , Susanne Ziegler , Sophie Laffont , Nikaïa Smith , Lise Chauveau , et al.
Journal of Immunology, 2015, 195 (11), pp.5327-36. ⟨10.4049/jimmunol.1501684⟩
Journal articles pasteur-01372393v1

Restoration of TRAIL-induced apoptosis in resistant human pancreatic cancer cells by a novel FAK inhibitor, PH11

P. Dao , N. Smith , Daniel Scott-Algara , C. Garbay , J.P. Herbeuval , et al.
Cancer Letters, 2015, 360 (1), pp.48-59. ⟨10.1016/j.canlet.2015.02.016⟩
Journal articles pasteur-02573704v1
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A monocyte/dendritic cell molecular signature of SARS-CoV2-related multisystem inflammatory syndrome in children (MIS-C) with severe myocarditis

Camille de Cevins , Marine Luka , Nikaïa Smith , Sonia Meynier , Aude Magérus , et al.
2021
Preprints, Working Papers, ... pasteur-03244400v1
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Dissecting human population variation in single-cell responses to SARS-CoV-2

Yann Aquino , Aurélie Bisiaux , Zhi Li , Mary O'Neill , Javier Mendoza-Revilla , et al.
Nature, 2023, 53 (8), pp.e2250307. ⟨10.1038/s41586-023-06422-9⟩
Journal articles pasteur-04186119v1
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Distinct systemic and mucosal immune responses during acute SARS-CoV-2 infection

Nikaïa Smith , Pedro Goncalves , Bruno Charbit , Ludivine Grzelak , Maxime Beretta , et al.
Nature Immunology, 2021, ⟨10.1038/s41590-021-01028-7⟩
Journal articles pasteur-03384279v1
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Early IFNβ secretion determines variable downstream IL-12p70 responses upon TLR4 activation

Celine Posseme , Alba Llibre , Bruno Charbit , Vincent Bondet , Vincent Rouilly , et al.
Cell Reports, 2022, 39 (13), pp.110989. ⟨10.1016/j.celrep.2022.110989⟩
Journal articles pasteur-03244390v2
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Immune profiling enables stratification of patients with active TB disease or M. tuberculosis infection

Darragh Duffy , Elisa Nemes , Alba Llibre , Vincent Rouilly , Munyaradzi Musvosvi , et al.
Clinical Infectious Diseases, 2020, ⟨10.1093/cid/ciaa1562⟩
Journal articles pasteur-03036505v1
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Defective activation and regulation of type I interferon immunity is associated with increasing COVID-19 severity

Nikaïa Smith , Céline Possémé , Vincent Bondet , Jamie Sugrue , Liam Townsend , et al.
Nature Communications, 2022, 13 (1), pp.7254. ⟨10.1038/s41467-022-34895-1⟩
Journal articles pasteur-03884236v1
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Identification of a small molecule that primes the type I interferon response to cytosolic DNA

Samira Khiar , Marianne Lucas-Hourani , Sebastien Nisole , Nikaia Smith , Olivier Helynck , et al.
Scientific Reports, 2017, 7 (1), pp.2561. ⟨10.1038/s41598-017-02776-z⟩
Journal articles pasteur-01570224v1
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Inborn errors of type I IFN immunity in patients with life-threatening COVID-19

Qian Zhang , Paul Bastard , Zhiyong Liu , Jérémie Le Pen , Marcela Moncada-Velez , et al.
Science, 2020, 370 (6515), pp.eabd4570. ⟨10.1126/science.abd4570⟩
Journal articles hal-02950982v1
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Environmental and genetic drivers of population differences in SARS-CoV-2 immune responses

Yann Aquino , Aurélie Bisiaux , Zhi Li , Mary O’neill , Javier Mendoza-Revilla , et al.
2023
Preprints, Working Papers, ... pasteur-03913748v1
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Interleukin‐7/Interferon axis drives T‐cell and salivary gland epithelial cell interactions in Sjögren’s syndrome

Elodie Rivière , Juliette Pascaud , Alexandre Virone , Anastasia Dupré , Bineta Ly , et al.
Arthritis & rheumatology, 2020, 73 (4), pp.631-640. ⟨10.1002/art.41558⟩
Journal articles pasteur-03036519v1