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Clostridial Binary Toxins: Iota and C2 Family Portraits

Bradley Stiles , Darran J Wigelsworth , Michel Popoff , Holger Barth
Frontiers in Cellular and Infection Microbiology, 2011, 1 (11), ⟨10.3389/fcimb.2011.00011⟩
Journal articles pasteur-01791344v1

FK506-binding protein 51 interacts with Clostridium botulinum C2 toxin and FK506 inhibits membrane translocation of the toxin in mammalian cells

Eva Kaiser , Natalie Böhm , Katharina Ernst , Simon Langer , Carsten Schwan , et al.
Cellular Microbiology, 2012, 14 (8), pp.1193 - 1205. ⟨10.1111/j.1462-5822.2012.01788.x⟩
Journal articles pasteur-01762818v1
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Cyclophilin-Facilitated Membrane Translocation as Pharmacological Target to Prevent Intoxication of Mammalian Cells by Binary Clostridial Actin ADP-Ribosylated Toxins

Katharina Ernst , Simon Langer , Eva Kaiser , Christian Osseforth , Jens Michaelis , et al.
Journal of Molecular Biology, 2015, 427 (6), pp.1224 - 1238. ⟨10.1016/j.jmb.2014.07.013⟩
Journal articles pasteur-01768428v1

Membrane Translocation of Binary Actin-ADP-Ribosylating Toxins from Clostridium difficile and Clostridium perfringens Is Facilitated by Cyclophilin A and Hsp90

Eva Kaiser , Claudia Kroll , Katharina Ernst , Carsten Schwan , Michel Popoff , et al.
Infection and Immunity, 2011, 79 (10), pp.3913 - 3921. ⟨10.1128/IAI.05372-11⟩
Journal articles pasteur-01762530v1

Revisiting an old antibiotic: bacitracin neutralizes binary bacterial toxins and protects cells from intoxication

Leonie Schnell , Ina Felix , Bastian Müller , Mirko Sadi , Franziska von Bank , et al.
FASEB Journal, 2019, 33 (4), pp.5755-5771. ⟨10.1096/fj.201802453R⟩
Journal articles pasteur-02453905v1
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CD44 Promotes Intoxication by the Clostridial Iota-Family Toxins

Darran J Wigelsworth , Gordon Ruthel , Leonie Schnell , Peter Herrlich , Josip Blonder , et al.
PLoS ONE, 2012, 7 (12), pp.e51356. ⟨10.1371/journal.pone.0051356⟩
Journal articles pasteur-01764029v1
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Tailored ß-Cyclodextrin Blocks the Translocation Pores of Binary Exotoxins from C. Botulinum and C. Perfringens and Protects Cells from Intoxication

Ekaterina M Nestorovich , Vladimir A Karginov , Michel Popoff , Sergey M Bezrukov , Holger Barth
PLoS ONE, 2011, 6 (8), pp.e23927. ⟨10.1371/journal.pone.0023927⟩
Journal articles pasteur-01762496v1
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Hsp70 facilitates trans-membrane transport of bacterial ADP-ribosylating toxins into the cytosol of mammalian cells

Katharina Ernst , Johannes Schmid , Matthias Beck , Marlen Hägele , Meike Hohwieler , et al.
Scientific Reports, 2017, 7 (1), pp.2724. ⟨10.1038/s41598-017-02882-y⟩
Journal articles pasteur-01820496v1
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A novel Hsp70 inhibitor prevents cell intoxication with the actin ADP-ribosylating Clostridium perfringens iota toxin

Katharina Ernst , Markus Liebscher , Sebastian Mathea , Anton Granzhan , Johannes Schmid , et al.
Scientific Reports, 2016, 6 (1), pp.20301. ⟨10.1038/srep20301⟩
Journal articles pasteur-01783777v1
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Clostridium perfringens Epsilon Toxin: A Malevolent Molecule for Animals and Man?

Bradley Stiles , Gillian Barth , Holger Barth , Michel Popoff
Toxins, 2013, Special Issue Enterotoxins: Microbial Proteins and Host Cell Dysregulation, 5 (11), pp.2138 - 2160. ⟨10.3390/toxins5112138⟩
Journal articles pasteur-01793395v1

Human alpha-defensin-1 protects cells from intoxication with Clostridium perfringens iota toxin

Stephan Fischer , Michel R. Popoff , Holger Barth
Pathogens and Disease, 2018, 76 (2), ⟨10.1093/femspd/fty022⟩
Journal articles pasteur-02448798v1
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Clostridium and Bacillus Binary Enterotoxins: Bad for the Bowels, and Eukaryotic Being

Bradley Stiles , Kisha Pradhan , Jodie Fleming , Ramar Perumal Samy , Holger Barth , et al.
Toxins, 2014, Special Issue: Enterotoxins: Microbial Proteins and Host Cell Dysregulation, 6 (9), pp.2626 - 2656. ⟨10.3390/toxins6092626⟩
Journal articles pasteur-01797042v1