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authFullName_s : Séverine Derbré

Highly cytotoxic and neurotoxic acetogenins of the Annonaceae: New putative biological targets of squamocin detected by activity-based protein profiling.

Séverine Derbré , Sophie Gil , Myriam Taverna , Céline Boursier , Valérie Nicolas , et al.
Bioorganic and Medicinal Chemistry Letters, 2008, epub ahead of print. ⟨10.1016/j.bmcl.2008.09.091⟩
Journal articles istex hal-00348099v1

Annonaceous acetogenins: the hydroxyl groups and THF rings are crucial structural elements for targeting the mitochondria, demonstration with the synthesis of fluorescent squamocin analogues.

Séverine Derbré , Gaël Roué , Erwan Poupon , Santos A Susin , Reynald Hocquemiller
ChemBioChem, 2005, 6 (6), pp.979-82. ⟨10.1002/cbic.200400396⟩
Journal articles istex pasteur-00193614v1

Semisynthesis and screening of a small library of pro-apoptotic squamocin analogues: selection and study of a benzoquinone hybrid with an improved biological profile.

Séverine Derbré , Romain Duval , Gaël Roué , Aurelio Garofano , Erwan Poupon , et al.
ChemMedChem, 2006, 1 (1), pp.118-29. ⟨10.1002/cmdc.200500011⟩
Journal articles istex pasteur-00165688v1