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authFullName_s : Patrice Vachette

SEC-SAXS and HDX-MS: A powerful combination. The case of the calcium-binding domain of a bacterial toxin

Darragh O'Brien , Sebastien Brier , Daniel Ladant , Dominique Durand , Alexandre Chenal , et al.
Biotechnology and Applied Biochemistry, 2018, 65 (1), pp.62-68. ⟨10.1002/bab.1577⟩
Journal articles hal-02329435v1
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Calmodulin fishing with a structurally disordered bait triggers CyaA catalysis

Darragh P. O'Brien , Dominique Durand , Alexis Voegele , Véronique Hourdel , Marilyne Davi , et al.
PLoS Biology, 2017, 15 (12), pp.e2004486. ⟨10.1371/journal.pbio.2004486⟩
Journal articles hal-02294928v1
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A High‐Affinity Calmodulin‐Binding Site in the CyaA Toxin Translocation Domain is Essential for Invasion of Eukaryotic Cells

Alexis Voegele , Mirko Sadi , Darragh Patrick O'Brien , Pauline Gehan , Dorothée Raoux‐barbot , et al.
Advanced Science, 2021, pp.2003630. ⟨10.1002/advs.202003630⟩
Journal articles pasteur-03211832v1

Translocation and calmodulin-activation of the adenylate cyclase toxin (CyaA) of Bordetella pertussis

Alexis Voegele , Darragh P. O'Brien , Orso Subrini , Nicolas Sapay , Sara E. Cannella , et al.
Pathogens and Disease, 2018, 76 (8), pp.fty085. ⟨10.1093/femspd/fty085⟩
Journal articles hal-02184809v1

X-ray structure of the pestivirus NS3 helicase and its conformation in solution.

M Alejandra Tortorici , Stéphane Duquerroy , Jane Kwok , Clemens Vonrhein , Javier Perez , et al.
Journal of Virology, 2015, 89 (8), pp.4356-71. ⟨10.1128/JVI.03165-14⟩
Journal articles hal-01449292v1

Calcium-dependent disorder-to-order transitions are central to the secretion and folding of the CyaA toxin of Bordetella pertussis, the causative agent of whooping cough

Darragh P. O'Brien , Ana Cristina Sotomayor Perez , Johanna Karst , Sara E. Cannella , Véronique Yvette Ntsogo Enguéné , et al.
Journal articles hal-02183106v1
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Structural models of intrinsically disordered and calcium-bound folded states of a protein adapted for secretion

Darragh P. O’brien , Belen Hernandez , Dominique Durand , Véronique Hourdel , Ana-Cristina Sotomayor-Pérez , et al.
Scientific Reports, 2016, 5, ⟨10.1038/srep14223⟩
Journal articles pasteur-01406897v1

Disorder-To-Order Transitions and Post-Translational Acylation Control the Folding and Activity of the Bordetella Pertussis CyaA Toxin

Darragh P. O'Brien , Alexis Voegele , Dorothee Raoux-Barbot , Marilyne Davi , Sara Cannella , et al.
Biophysical Journal, 2020, 118 (3), pp.197A--197A
Journal articles hal-02516165v1
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Stability, structural and functional properties of a monomeric, calcium-loaded adenylate cyclase toxin, CyaA, from Bordetella pertussis.

Sara E Cannella , Véronique Yvette Ntsogo Enguéné , Marilyne Davi , Christian Malosse , Ana Cristina Sotomayor Pérez , et al.
Scientific Reports, 2017, 7, pp.42065. ⟨10.1038/srep42065⟩
Journal articles pasteur-01508525v1
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Dynamics and structural changes of calmodulin upon interaction with the antagonist calmidazolium

Corentin Léger , Irène Pitard , Mirko Sadi , Nicolas Carvalho , Sébastien Brier , et al.
BMC Biology, 2022, 20 (1), pp.176. ⟨10.1186/s12915-022-01381-5⟩
Journal articles pasteur-03880614v1