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authFullName_s : Olivier Leclercq

Enrichment of Leishmania donovani ATP-binding proteins using a staurosporine capture compound.

Olivier Leclercq , Kathrin Bartho , Erik Duelsner , Lisa von Kleist , Pier Federico Gherardini , et al.
Journal of Proteomics, 2013, 86, pp.97-104. ⟨10.1016/j.jprot.2013.05.002⟩
Journal articles pasteur-01433419v1
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Etablissement d’une approche de déconvolution de cibles pour des composés leishmanicides Ecole Pratique des Hautes Etudes Mémoire préparé sous la direction de Gérald Späth, Najma Rachidi et Sylvie Demignot

Olivier Leclercq
Biochimie [q-bio.BM]. 2016
Master thesis hal-01468100v1
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Cyclosporin A treatment of Leishmania donovani reveals stage-specific functions of cyclophilins in parasite proliferation and viability

Wai-Lok Yau , Thierry Blisnick , Jean-François Taly , Manuela Helmer-Citterich , Cordelia Schiene-Fischer , et al.
PLoS Neglected Tropical Diseases, 2010, 4 (6), pp.e729. ⟨10.1371/journal.pntd.0000729⟩
Journal articles pasteur-01433566v1
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The Crystal Structure of the MAP Kinase LmaMPK10 from Leishmania Major Reveals Parasite-Specific Features and Regulatory Mechanisms.

Sofía Horjales , Dirk Schmidt-Arras , Ramiro Rodriguez Limardo , Olivier Leclercq , Gonzalo Obal , et al.
Structure, 2012, epub ahead of print. ⟨10.1016/j.str.2012.07.005⟩
Journal articles pasteur-00727033v1
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Transgenic analysis of the Leishmania MAP kinase MPK10 reveals an auto-inhibitory mechanism crucial for stage-regulated activity and parasite viability.

Mathieu Cayla , Najma Rachidi , Olivier Leclercq , Dirk Schmidt-Arras , Heidi Rosenqvist , et al.
PLoS Pathogens, 2014, 10 (9), pp.e1004347. ⟨10.1371/journal.ppat.1004347⟩
Journal articles pasteur-01109591v1
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From drug screening to target deconvolution: A target-based drug discovery pipeline using Leishmania casein kinase 1 isoform 2 to identify compounds with anti-leishmanial activity

Emilie Durieu , Eric Prina , Olivier Leclercq , Nassima Oumata , Nicolas Gaboriaud-Kolar , et al.
Antimicrobial Agents and Chemotherapy, 2016, ⟨10.1128/AAC.00021-16⟩
Journal articles hal-01299756v1

Adaptation of a 2D in-gel kinase assay to trace phosphotransferase activities in the human pathogen Leishmania donovani

Dirk Schmidt-Arras , Olivier Leclercq , Pier Federico Gherardini , Manuela Helmer-Citterich , Wolfgang Faigle , et al.
Journal of Proteomics, 2011, 74 (9), pp.1644-1651. ⟨10.1016/j.jprot.2011.03.024⟩
Journal articles pasteur-01433562v1

Pharmacological assessment defines Leishmania donovani casein kinase 1 as a drug target and reveals important functions in parasite viability and intracellular infection

Najma Rachidi , Jean François Taly , Emilie Durieu , Olivier Leclercq , Nathalie Aulner , et al.
Antimicrobial Agents and Chemotherapy, 2014, 58 (3), pp.1501-1515. ⟨10.1128/AAC.02022-13⟩
Journal articles pasteur-01433412v1
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Probing druggability and biological function of essential proteins in Leishmania combining facilitated null mutant and plasmid shuffle analyses

Mariko Dacher , Miguel A Morales , Pascale Pescher , Olivier Leclercq , Najma Rachidi , et al.
Molecular Microbiology, 2014, 93, pp.146-166. ⟨10.1111/mmi.12648⟩
Journal articles hal-01178772v1
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In vitro identification of imidazo[1,2-a]pyrazine-based antileishmanial agents and evaluation of L. major casein kinase 1 inhibition

Marc-Antoine Bazin , Sandrine Cojean , Fabrice Pagniez , Guillaume Bernadat , Christian Cavé , et al.
European Journal of Medicinal Chemistry, 2021, 210, pp.112956. ⟨10.1016/j.ejmech.2020.112956⟩
Journal articles pasteur-03108849v1
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Ectopic Expression of AID in a Non-B Cell Line Triggers A∶T and G:C Point Mutations in Non-Replicating Episomal Vectors

Tihana Jovanic , Benjamin Roche , Géraldine Attal-Bonnefoy , Olivier Leclercq , François Rougeon
PLoS ONE, 2008, 3 (1), pp.e1480. ⟨10.1371/journal.pone.0001480⟩
Journal articles hal-04194767v1