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SARS-CoV-2 Nsp3 unique domain SUD interacts with guanine quadruplexes and G4-ligands inhibit this interaction
Marc Lavigne
,
Olivier Helynck
,
Pascal Rigolet
,
Rofia Boudria-Souilah
,
Mireille Nowakowski
,
et al.
Journal articles
hal-03281130v1
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Inhibition of the inflammatory response to stress by targeting interaction between PKR and its cellular activator PACT
Stéphanie Dabo
,
Patrick Maillard
,
Milagros Collados Rodriguez
,
Marianne Doré Hansen
,
Sabrina Mazouz
,
et al.
Journal articles
pasteur-01682150v1
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A Novel Polyaminocarboxylate Compound To Treat Murine Pulmonary Aspergillosis by Interfering with Zinc Metabolism
Paris Laskaris
,
Rocío Vicentefranqueira
,
Olivier Helynck
,
Grégory Jouvion
,
José Antonio Calera
,
et al.
Journal articles
pasteur-01968421v1
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High-throughput Screening for Broad-spectrum Chemical Inhibitors of RNA Viruses
Marianne Lucas-Hourani
,
Hélène Munier-Lehmann
,
Olivier Helynck
,
Anastassia Komarova
,
Philippe Desprès
,
et al.
Journal of visualized experiments : JoVE, 2014, 87, pp.e51222. ⟨10.3791/51222⟩
Journal articles
pasteur-01113538v1
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Steroid hormone catabolites activate the pyrin inflammasome through a non-canonical mechanism
Flora Magnotti
,
Daria Chirita
,
Sarah Dalmon
,
Amandine Martin
,
Pauline Bronnec
,
et al.
Journal articles
hal-03811426v1
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Stimulation of the antiviral innate immune response by pyrimidine biosynthesis inhibitors: a surprise of phenotypic screening
Pierre-Olivier Vidalain
,
Marianne Lucas-Hourani
,
Olivier Helynck
,
Frédéric Tangy
,
Hélène Munier-Lehmann
Journal articles
pasteur-01174082v1
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Original 2-(3-Alkoxy-1H-pyrazol-1-yl)azines Inhibitors of Human Dihydroorotate Dehydrogenase (DHODH).
Marianne Lucas-Hourani
,
Hélène Munier-Lehmann
,
Farah El Mazouni
,
Nicholas A Malmquist
,
Jane Harpon
,
et al.
Journal articles
pasteur-01170546v1
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Original 2-(3-Alkoxy-1H-pyrazol-1-yl)pyrimidine Derivatives as Inhibitors of Human Dihydroorotate Dehydrogenase (DHODH)
Hélène Munier-Lehmann
,
Marianne Lucas-Hourani
,
Sandrine Guillou
,
Olivier Helynck
,
Gigliola Zanghi
,
et al.
Journal articles
pasteur-01101526v1
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High content analysis of primary macrophages hosting proliferating Leishmania amastigotes: application to anti-leishmanial drug discovery.
Nathalie Aulner
,
Anne Danckaert
,
Eline Rouault-Hardoin
,
Julie Desrivot
,
Olivier Helynck
,
et al.
Journal articles
pasteur-01433415v1
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Synthesis and inhibitory activity of thymidine analogues targeting Mycobacterium tuberculosis thymidine monophosphate kinase.
Sara van Poecke
,
Hélène Munier-Lehmann
,
Olivier Helynck
,
Matheus Froeyen
,
Serge van Calenbergh
Journal articles
pasteur-00645423v1
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Discovery of Bis-Imidazoline Derivatives as New CXCR4 Ligands
Zhicheng Zhou
,
Isabelle Staropoli
,
Anne Brelot
,
Peggy Suzanne
,
Aurélien Lesnard
,
et al.
Journal articles
pasteur-04096396v1
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Nitazoxanide Analogs Require Nitroreduction for Antimicrobial Activity in Mycobacterium smegmatis
Maria Buchieri
,
Mena Cimino
,
Sonia Rebollo-Ramirez
,
Claire Beauvineau
,
Alessandro Cascioferro
,
et al.
Journal articles
pasteur-01693404v1
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Inhibition of Pyrimidine Biosynthesis Pathway Suppresses Viral Growth through Innate Immunity
Marianne Lucas-Hourani
,
Daniel Dauzonne
,
Pierre Jorda
,
Gaëlle Cousin
,
Alexandru Lupan
,
et al.
Journal articles
pasteur-01113535v1
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Original Chemical Series of Pyrimidine Biosynthesis Inhibitors That Boost the Antiviral Interferon Response
Marianne Lucas-Hourani
,
Daniel Dauzonne
,
Hélène Munier-Lehmann
,
Samira Khiar
,
Sébastien Nisole
,
et al.
Journal articles
pasteur-01693518v1
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Synergy of the antibiotic colistin with echinocandin antifungals in Candida species.
Ute Zeidler
,
Marie-Elisabeth Bougnoux
,
Alexandru Lupan
,
Olivier Helynck
,
Antonia Doyen
,
et al.
Journal articles
pasteur-00849830v1
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High seroprevalence but short-lived immune response to SARS-CoV-2 infection in Paris
François Anna
,
Sophie Goyard
,
Ana Ines Lalanne
,
Fabien Nevo
,
Marion Gransagne
,
et al.
Journal articles
pasteur-02988663v2
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Identification of a small molecule that primes the type I interferon response to cytosolic DNA
Samira Khiar
,
Marianne Lucas-Hourani
,
Sebastien Nisole
,
Nikaia Smith
,
Olivier Helynck
,
et al.
Journal articles
pasteur-01570224v1
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First-in-class allosteric inhibitors of bacterial IMPDHs
Thomas Alexandre
,
Alexandru Lupan
,
Olivier Helynck
,
Sophie Vichier-Guerre
,
Laurence Dugué
,
et al.
Journal articles
pasteur-02125232v1
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Prevalence of SARS-CoV-2 antibodies in France: results from nationwide serological surveillance
Stéphane Le Vu
,
Gabrielle Jones
,
François Anna
,
Thierry Rose
,
Jean-Baptiste Richard
,
et al.
Journal articles
pasteur-03147098v2
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