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authFullName_s : Najma Rachidi

The low complexity regions in the C-terminus are essential for the subcellular localisation of Leishmania casein kinase 1 but not for its activity

Daniel Martel , Stewart Pine , Katharina Bartsch , Joachim Clos , Gerald Späth , et al.
Preprints, Working Papers, ... pasteur-02874585v1
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CRISPR in Parasitology: Not Exactly Cut and Dried!

Jessica Bryant , Sebastian Baumgarten , Lucy Glover , Sebastian Hutchinson , Najma Rachidi
Trends in Parasitology, 2019, 35 (6), pp.409-422. ⟨10.1016/⟩
Journal articles pasteur-02874588v1

Apoptotic marker expression in the absence of cell death in staurosporine-treated Leishmania donovani

Aude L. Foucher , Najma Rachidi , Sarah Gharbi , Thierry Blisnick , Philippe Bastin , et al.
Antimicrobial Agents and Chemotherapy, 2013, 57 (3), pp.1252-1261. ⟨10.1128/AAC.01983-12⟩
Journal articles pasteur-01433417v1
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Released Parasite-Derived Kinases as Novel Targets for Antiparasitic Therapies

Anne Silvestre , Sharvani Shrinivas Shintre , Najma Rachidi
Frontiers in Cellular and Infection Microbiology, 2022, 12, 12 p. ⟨10.3389/fcimb.2022.825458⟩
Journal articles hal-03681384v1
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Identification of the Host Substratome of Leishmania-Secreted Casein Kinase 1 Using a SILAC-Based Quantitative Mass Spectrometry Assay

Despina Smirlis , Florent Dingli , Valentin Sabatet , Aileen Roth , Uwe Knippschild , et al.
Frontiers in Cell and Developmental Biology, 2022, 9, pp.800098. ⟨10.3389/fcell.2021.800098⟩
Journal articles pasteur-03524218v1
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Transgenic analysis of the Leishmania MAP kinase MPK10 reveals an auto-inhibitory mechanism crucial for stage-regulated activity and parasite viability.

Mathieu Cayla , Najma Rachidi , Olivier Leclercq , Dirk Schmidt-Arras , Heidi Rosenqvist , et al.
PLoS Pathogens, 2014, 10 (9), pp.e1004347. ⟨10.1371/journal.ppat.1004347⟩
Journal articles pasteur-01109591v1

Structure, regulation, and (patho-)physiological functions of the stress-induced protein kinase CK1 delta (CSNK1D)

Pengfei Xu , Chiara Ianes , Fabian Gärtner , Congxing Liu , Timo Burster , et al.
Gene, 2019, 715, pp.144005. ⟨10.1016/j.gene.2019.144005⟩
Journal articles pasteur-02874586v1
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From drug screening to target deconvolution: A target-based drug discovery pipeline using Leishmania casein kinase 1 isoform 2 to identify compounds with anti-leishmanial activity

Emilie Durieu , Eric Prina , Olivier Leclercq , Nassima Oumata , Nicolas Gaboriaud-Kolar , et al.
Antimicrobial Agents and Chemotherapy, 2016, ⟨10.1128/AAC.00021-16⟩
Journal articles hal-01299756v1
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A touch of Zen: post-translational regulation of the Leishmania stress response

Gerald F Späth , Sima Drini , Najma Rachidi
Cellular Microbiology, 2015, 17 (5), pp.632-638. ⟨10.1111/cmi.12440⟩
Journal articles pasteur-01433407v1
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Studying two complementary infection models to identify common mechanisms of intracellular parasite survival: The roles of Leishmania and Eimeria exo-kinases in subversion of host cell signalling

Sharvani Shintre , Florent Dingli , Damarys Loew , Anne Silvestre , Najma Rachidi
EMBO Workshop : New frontiers in host-parasite interactions, from cell to organism, Oct 2022, Six-Fours-Les-Plages, France.
Conference poster hal-04126119v1
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The enemy within: Targeting host–parasite interaction for antileishmanial drug discovery

Suzanne Lamotte , Gerald F Späth , Najma Rachidi , Eric Prina
PLoS Neglected Tropical Diseases, 2017, 11 (6), pp.e0005480. ⟨10.1371/journal.pntd.0005480⟩
Journal articles pasteur-01570238v1
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Dangerous Duplicity: The Dual Functions of Casein Kinase 1 in Parasite Biology and Host Subversion

Najma Rachidi , Uwe Knippschild , Gerald F Späth
Frontiers in Cellular and Infection Microbiology, 2021, 11, pp.655700. ⟨10.3389/fcimb.2021.655700⟩
Journal articles pasteur-03402709v1
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SILAC-based quantitative proteomics reveals pleiotropic, phenotypic modulation in primary murine macrophages infected with the protozoan pathogen Leishmania donovani

Despina Smirlis , Florent Dingli , Pascale Pescher , Eric Prina , Damarys Loew , et al.
Journal of Proteomics, 2020, 213, pp.103617. ⟨10.1016/j.jprot.2019.103617⟩
Journal articles pasteur-02750320v1
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Species- and Strain-Specific Adaptation of the HSP70 Super Family in Pathogenic Trypanosomatids

Sima Drini , Alexis Criscuolo , Pierre Lechat , Hideo Imamura , Tomáš Skalický , et al.
Genome Biology and Evolution, 2016, 8 (6), pp.1980-1995. ⟨10.1093/gbe/evw140⟩
Journal articles pasteur-02635182v1

The kinase domain of CK1δ can be phosphorylated by Chk1

Thomas Böhm , Zhigang Meng , Philipp Haas , Doris Henne-Bruns , Najma Rachidi , et al.
Bioscience, Biotechnology and Biochemistry, 2019, 83 (9), pp.1663-1675. ⟨10.1080/09168451.2019.1617105⟩
Journal articles pasteur-02874589v1

Pharmacological assessment defines Leishmania donovani casein kinase 1 as a drug target and reveals important functions in parasite viability and intracellular infection

Najma Rachidi , Jean François Taly , Emilie Durieu , Olivier Leclercq , Nathalie Aulner , et al.
Antimicrobial Agents and Chemotherapy, 2014, 58 (3), pp.1501-1515. ⟨10.1128/AAC.02022-13⟩
Journal articles pasteur-01433412v1
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Leishmania Donovani 90 kD Heat Shock Protein - Impact of Phosphosites on Parasite Fitness, Infectivity and Casein Kinase Affinity

Antje Hombach-Barrigah , Katharina Bartsch , Despina Smirlis , Heidi Rosenqvist , Andrea Macdonald , et al.
Scientific Reports, 2019, 9 (1), pp.5074. ⟨10.1038/s41598-019-41640-0⟩
Journal articles pasteur-02874587v1
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Probing druggability and biological function of essential proteins in Leishmania combining facilitated null mutant and plasmid shuffle analyses

Mariko Dacher , Miguel A Morales , Pascale Pescher , Olivier Leclercq , Najma Rachidi , et al.
Molecular Microbiology, 2014, 93, pp.146-166. ⟨10.1111/mmi.12648⟩
Journal articles hal-01178772v1
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Characterisation of Casein Kinase 1.1 in Leishmania donovani Using the CRISPR Cas9 Toolkit

Daniel Martel , Tom Beneke , Eva Gluenz , Gerald F Späth , Najma Rachidi
BioMed Research International , 2017, 2017, pp.4635605. ⟨10.1155/2017/4635605⟩
Journal articles pasteur-01974292v1
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In vitro identification of imidazo[1,2-a]pyrazine-based antileishmanial agents and evaluation of L. major casein kinase 1 inhibition

Marc-Antoine Bazin , Sandrine Cojean , Fabrice Pagniez , Guillaume Bernadat , Christian Cavé , et al.
European Journal of Medicinal Chemistry, 2021, 210, pp.112956. ⟨10.1016/j.ejmech.2020.112956⟩
Journal articles pasteur-03108849v1