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The low complexity regions in the C-terminus are essential for the subcellular localisation of Leishmania casein kinase 1 but not for its activity
Daniel Martel
,
Stewart Pine
,
Katharina Bartsch
,
Joachim Clos
,
Gerald Späth
,
et al.
2020
Preprints, Working Papers, ...
pasteur-02874585v1
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CRISPR in Parasitology: Not Exactly Cut and Dried!
Jessica Bryant
,
Sebastian Baumgarten
,
Lucy Glover
,
Sebastian Hutchinson
,
Najma Rachidi
Journal articles
pasteur-02874588v1
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Apoptotic marker expression in the absence of cell death in staurosporine-treated Leishmania donovani
Aude L. Foucher
,
Najma Rachidi
,
Sarah Gharbi
,
Thierry Blisnick
,
Philippe Bastin
,
et al.
Journal articles
pasteur-01433417v1
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Released Parasite-Derived Kinases as Novel Targets for Antiparasitic Therapies
Anne Silvestre
,
Sharvani Shrinivas Shintre
,
Najma Rachidi
Journal articles
hal-03681384v1
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Identification of the Host Substratome of Leishmania-Secreted Casein Kinase 1 Using a SILAC-Based Quantitative Mass Spectrometry Assay
Despina Smirlis
,
Florent Dingli
,
Valentin Sabatet
,
Aileen Roth
,
Uwe Knippschild
,
et al.
Journal articles
pasteur-03524218v1
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Transgenic analysis of the Leishmania MAP kinase MPK10 reveals an auto-inhibitory mechanism crucial for stage-regulated activity and parasite viability.
Mathieu Cayla
,
Najma Rachidi
,
Olivier Leclercq
,
Dirk Schmidt-Arras
,
Heidi Rosenqvist
,
et al.
Journal articles
pasteur-01109591v1
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Structure, regulation, and (patho-)physiological functions of the stress-induced protein kinase CK1 delta (CSNK1D)
Pengfei Xu
,
Chiara Ianes
,
Fabian Gärtner
,
Congxing Liu
,
Timo Burster
,
et al.
Journal articles
pasteur-02874586v1
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From drug screening to target deconvolution: A target-based drug discovery pipeline using Leishmania casein kinase 1 isoform 2 to identify compounds with anti-leishmanial activity
Emilie Durieu
,
Eric Prina
,
Olivier Leclercq
,
Nassima Oumata
,
Nicolas Gaboriaud-Kolar
,
et al.
Journal articles
hal-01299756v1
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A touch of Zen: post-translational regulation of the Leishmania stress response
Gerald F Späth
,
Sima Drini
,
Najma Rachidi
Journal articles
pasteur-01433407v1
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Studying two complementary infection models to identify common mechanisms of intracellular parasite survival: The roles of Leishmania and Eimeria exo-kinases in subversion of host cell signalling
Sharvani Shintre
,
Florent Dingli
,
Damarys Loew
,
Anne Silvestre
,
Najma Rachidi
EMBO Workshop : New frontiers in host-parasite interactions, from cell to organism, Oct 2022, Six-Fours-Les-Plages, France.
Conference poster
hal-04126119v1
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The enemy within: Targeting host–parasite interaction for antileishmanial drug discovery
Suzanne Lamotte
,
Gerald F Späth
,
Najma Rachidi
,
Eric Prina
Journal articles
pasteur-01570238v1
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Dangerous Duplicity: The Dual Functions of Casein Kinase 1 in Parasite Biology and Host Subversion
Najma Rachidi
,
Uwe Knippschild
,
Gerald F Späth
Journal articles
pasteur-03402709v1
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SILAC-based quantitative proteomics reveals pleiotropic, phenotypic modulation in primary murine macrophages infected with the protozoan pathogen Leishmania donovani
Despina Smirlis
,
Florent Dingli
,
Pascale Pescher
,
Eric Prina
,
Damarys Loew
,
et al.
Journal articles
pasteur-02750320v1
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Species- and Strain-Specific Adaptation of the HSP70 Super Family in Pathogenic Trypanosomatids
Sima Drini
,
Alexis Criscuolo
,
Pierre Lechat
,
Hideo Imamura
,
Tomáš Skalický
,
et al.
Journal articles
pasteur-02635182v1
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The kinase domain of CK1δ can be phosphorylated by Chk1
Thomas Böhm
,
Zhigang Meng
,
Philipp Haas
,
Doris Henne-Bruns
,
Najma Rachidi
,
et al.
Journal articles
pasteur-02874589v1
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Pharmacological assessment defines Leishmania donovani casein kinase 1 as a drug target and reveals important functions in parasite viability and intracellular infection
Najma Rachidi
,
Jean François Taly
,
Emilie Durieu
,
Olivier Leclercq
,
Nathalie Aulner
,
et al.
Journal articles
pasteur-01433412v1
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Leishmania Donovani 90 kD Heat Shock Protein - Impact of Phosphosites on Parasite Fitness, Infectivity and Casein Kinase Affinity
Antje Hombach-Barrigah
,
Katharina Bartsch
,
Despina Smirlis
,
Heidi Rosenqvist
,
Andrea Macdonald
,
et al.
Journal articles
pasteur-02874587v1
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Probing druggability and biological function of essential proteins in Leishmania combining facilitated null mutant and plasmid shuffle analyses
Mariko Dacher
,
Miguel A Morales
,
Pascale Pescher
,
Olivier Leclercq
,
Najma Rachidi
,
et al.
Journal articles
hal-01178772v1
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Characterisation of Casein Kinase 1.1 in Leishmania donovani Using the CRISPR Cas9 Toolkit
Daniel Martel
,
Tom Beneke
,
Eva Gluenz
,
Gerald F Späth
,
Najma Rachidi
Journal articles
pasteur-01974292v1
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In vitro identification of imidazo[1,2-a]pyrazine-based antileishmanial agents and evaluation of L. major casein kinase 1 inhibition
Marc-Antoine Bazin
,
Sandrine Cojean
,
Fabrice Pagniez
,
Guillaume Bernadat
,
Christian Cavé
,
et al.
Journal articles
pasteur-03108849v1
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