Convergent synthesis of the methyl glycosides of a tetra- and a pentasaccharide fragment of the Shigella flexneri serotype 2a O-specific polysaccharide
Fabienne Ségat-Dioury
,
Laurence A Mulard
Journal articles
istex
hal-02509428v1
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Exploratory N‐Protecting Group Manipulation for the Total Synthesis of Zwitterionic Shigella sonnei Oligosaccharides
Debashis Dhara
,
Laurence A Mulard
Journal articles
pasteur-03722328v1
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Non-stoichiometric O-acetylation of Shigella flexneri 2a O-specific polysaccharide: synthesis and antigenicity
Charles Gauthier
,
Pierre Chassagne
,
Francois-Xavier Theillet
,
Catherine Guerreiro
,
Francoise Thouron
,
et al.
Journal articles
hal-01172002v1
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Concise synthesis of di- and trisaccharides related to the O-antigens from Shigella flexneri serotypes 6 and 6a, based on late stage mono-O-acetylation and/or site-selective oxidation
Pierre Chassagne
,
Laurent Raibaut
,
Catherine Guerreiro
,
Laurence A Mulard
Journal articles
pasteur-02043363v1
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Combination of High-Resolution Multistage Ion Mobility and Tandem MS with High Energy of Activation to Resolve the Structure of Complex Chemoenzymatically Synthesized Glycans
David Ropartz
,
Mathieu Fanuel
,
Simon Ollivier
,
Adrien Lissarrague
,
Mounir Benkoulouche
,
et al.
Journal articles
hal-03573196v1
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Effects of backbone substitutions on the conformational behavior of Shigella flexneri O-antigens: implications for vaccine strategy.
François-Xavier Theillet
,
Catherine Simenel
,
Catherine Guerreiro
,
Armelle Phalipon
,
Laurence A Mulard
,
et al.
Journal articles
hal-00550773v1
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Investigation towards bivalent chemically defined glycoconjugate immunogens prepared from acid-detoxified lipopolysaccharide of Vibrio cholerae O1, serotype Inaba.
Cyrille Grandjean
,
Alain Boutonnier
,
Bruno Dassy
,
Jean-Michel Fournier
,
Laurence A Mulard
Journal articles
pasteur-00335927v1
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Vaccination against shigellosis: is it the path that is difficult or is it the difficult that is the path?
Armelle Phalipon
,
Laurence A Mulard
,
Philippe Sansonetti
Journal articles
istex
pasteur-00335872v1
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Bacterial polysaccharides as major surface antigens: interest in O-acetyl substitutions
Laurence A Mulard
Carbohydrate Chemistry : chemical and biological approaches , 43, Royal Society of Chemistry (London), 2017, 978-1-78801-003-0 (print) ; 978-1-78801-064-1 (PDF) ; 978-1-78801-409-0 (ePUB).
⟨10.1039/9781788010641-00071⟩
Book sections
pasteur-01851517v1
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Toward a Multivalent Synthetic Oligosaccharide-Based Conjugate Vaccine against Shigella: State-of-the-Art for a Monovalent Prototype and Challenges
Armelle Phalipon
,
Laurence A Mulard
Journal articles
pasteur-03699792v1
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Preparation of synthetic glycoconjugates as potential vaccines against Shigella flexneri serotype 2a disease.
Karen Wright
,
Catherine Guerreiro
,
Isabelle Laurent
,
Françoise Baleux
,
Laurence A Mulard
Journal articles
pasteur-00166853v1
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Synthesis of two linear PADRE conjugates bearing a deca- or pentadecasaccharide B epitope as potential synthetic vaccines against Shigella flexneri serotype 2a infection.
Frédéric Bélot
,
Catherine Guerreiro
,
Françoise Baleux
,
Laurence A Mulard
Journal articles
istex
pasteur-00166810v1
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Efficient Iterative Synthesis of O-Acetylated Tri- to Pentadecasaccharides Related to the Lipopolysaccharide of Shigella flexneri Type 3 a through Di- and Trisaccharide Glycosyl Donors
Zhaoyu Hu
,
Aileen F Bongat White
,
Laurence A Mulard
Journal articles
pasteur-01627935v1
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Computer-aided engineering of a branching sucrase for the glucodiversification of a tetrasaccharide precursor of S. flexneri antigenic oligosaccharides
Mounir Benkoulouche
,
Akli Ben Imeddourene
,
Louis-Antoine Barel
,
Dorian Lefebvre
,
Mathieu Fanuel
,
et al.
Journal articles
hal-03382404v1
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Multigram synthesis of an orthogonally-protected pentasaccharide for use as a glycan precursor in a Shigella flexneri 3a conjugate vaccine: application to a ready-for-conjugation decasaccharide
Johan Cornil
,
Zhaoyu Hu
,
Marion Bouchet
,
Laurence A Mulard
Journal articles
pasteur-03722329v1
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Synthesis of branched tri-to pentasaccharides representative of fragments of Shigella flexneri serotypes 3a and/or X O-antigens
Julien Boutet
,
Catherine Guerreiro
,
Laurence A Mulard
Journal articles
istex
pasteur-00336071v1
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Rational design and immunogenicity of liposome-based diepitope constructs: application to synthetic oligosaccharides mimicking the Shigella flexneri 2a O-antigen.
Fatouma Said Hassane
,
Armelle Phalipon
,
Myriam Tanguy
,
Catherine Guerreiro
,
Frédéric Bélot
,
et al.
Journal articles
istex
hal-00414241v1
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Acyclic phosphonate nucleotides and human adenylate kinases: impact of a borano group on alpha-P position.
D. Topalis
,
K. Alvarez
,
K. Barral
,
Hélène Munier-Lehmann
,
B. Schneider
,
et al.
Journal articles
pasteur-00316017v1
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Structures of synthetic O-antigen fragments from serotype 2a Shigella flexneri in complex with a protective monoclonal antibody.
B. Vulliez-Le Normand
,
F. A. Saul
,
Armelle Phalipon
,
F. Bélot
,
C. Guerreiro
,
et al.
Proceedings of the National Academy of Sciences of the United States of America , 2008, 105 (29), pp.9976-81.
⟨10.1073/pnas.0801711105⟩
Journal articles
pasteur-00336029v1
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Programmed chemo-enzymatic synthesis of the oligosaccharide component of a carbohydrate-based antibacterial vaccine candidate
Stephane Salamone
,
Catherine Guerreiro
,
Emmanuelle Cambon
,
Isabelle André
,
Magali Remaud Simeon
,
et al.
Journal articles
hal-01269073v1
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A Synthetic Carbohydrate Conjugate Vaccine Candidate against Shigellosis: Improved Bioconjugation and Impact of Alum on Immunogenicity.
Robert M F van Der Put
,
Tae Hee Kim
,
Catherine Guerreiro
,
Françoise Thouron
,
Peter Hoogerhout
,
et al.
Journal articles
pasteur-01350027v1
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Convergent synthesis, NMR and conformational analysis of tetra-and petasaccharide haptens of the Shigella flexneri serotype 5a O-specific polysaccharide
Laurence A Mulard
,
Marie-Jeanne Clément
,
Anne Imberty
,
Muriel Delepierre
Journal articles
istex
pasteur-00371353v1
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Applying Pairwise Combinations of Amino Acid Mutations for Sorting Out Highly Efficient Glucosylation Tools for Chemo-Enzymatic Synthesis of Bacterial Oligosaccharides
Elise Champion
,
Frédéric Guerin
,
Claire Moulis
,
Sophie Barbe
,
Thu Hoai Tran
,
et al.
Journal of the American Chemical Society , 2012, 134 (45), pp.18677 - 18688.
⟨10.1021/ja306845b⟩
Journal articles
hal-03003058v1
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Characterization of functional oligosaccharide mimics of the Shigella flexneri serotype 2a O-antigen: implications for the development of a chemically defined glycoconjugate vaccine.
Armelle Phalipon
,
Corina Costachel
,
Cyrille Grandjean
,
Audrey Thuizat
,
Catherine Guerreiro
,
et al.
Journal articles
pasteur-00166117v1
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Structural mimicry of O-antigen by a peptide revealed in a complex with an antibody raised against Shigella flexneri serotype 2a.
François-Xavier Theillet
,
Frederick A Saul
,
Brigitte Vulliez-Le Normand
,
Sylviane Hoos
,
Franco Felici
,
et al.
Journal articles
istex
hal-00414251v1
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Conformational studies of the O-specific polysaccharide of Shigella flexneri 5a and of four related synthetic pentasaccharide fragments using NMR and molecular modeling.
Marie-Jeanne Clément
,
Anne Imberty
,
Armelle Phalipon
,
Serge Pérez
,
Catherine Simenel
,
et al.
Journal articles
pasteur-00369608v1
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Design of alpha-transglucosidases of controlled specificity for programmed chemoenzymatic synthesis of antigenic oligosaccharides.
Elise Champion
,
Isabelle André
,
Claire Moulis
,
Julien Boutet
,
Karine Descroix
,
et al.
Journal articles
hal-00414248v1
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Efficient synthesis of six tri- to hexasaccharide fragments of Shigella flexneri serotypes 3a and/or X O-antigen, including a study on acceptors containing N-trichloroacetylglucosamine versus N-acetylglucosamine.
Julien Boutet
,
Catherine Guerreiro
,
Laurence A Mulard
Journal articles
hal-00414254v1
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A synthetic carbohydrate-protein conjugate vaccine candidate against Shigella flexneri 2a infection.
Armelle Phalipon
,
Myriam Tanguy
,
Cyrille Grandjean
,
Catherine Guerreiro
,
Frédéric Bélot
,
et al.
Journal articles
hal-00414256v1
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Safety and immunogenicity of a synthetic carbohydrate conjugate vaccine against Shigella flexneri 2a in healthy adult volunteers: a phase 1, dose-escalating, single-blind, randomised, placebo-controlled study
Dani Cohen
,
Jacob Atsmon
,
Cécile Artaud
,
Shiri Meron-Sudai
,
Marie-Lise Gougeon
,
et al.
Journal articles
pasteur-03699905v1
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