Search - Institut Pasteur Access content directly

Filter your results

13 Results
authFullName_s : Christel Brou
Image document

The Translation Initiation Factor 3F (eIF3f) Exhibits a Deubiquitinase Activity Regulating Notch Activation

Julien Moretti , Patricia Chastagner , Stefano Gastaldello , Sara F. Heuss , Annette M. Dirac , et al.
PLoS Biology, 2010, 8 (11), pp.e1000545. ⟨10.1371/journal.pbio.1000545⟩
Journal articles pasteur-00539184v1
Image document

Functional interaction between SEL-10, an F-box protein, and the nuclear form of activated Notch1 receptor.

Neetu Gupta-Rossi , Odile Le Bail , Hedva Gonen , Christel Brou , Frédérique Logeat , et al.
Journal of Biological Chemistry, 2001, 276 (37), pp.34371-8. ⟨10.1074/jbc.M101343200⟩
Journal articles pasteur-00583295v1
Image document

Ligand-activated Notch undergoes DTX4-mediated ubiquitylation and bilateral endocytosis before ADAM10 processing

Patricia Chastagner , Eric Rubinstein , Christel Brou
Science Signaling, 2017, 10 (483), pp.aag2989. ⟨10.1126/scisignal.aag2989⟩
Journal articles hal-04002682v1
Image document

Fate and propagation of endogenously formed Tau aggregates in neuronal cells

Patricia Chastagner , Frida Loria , Jessica Vargas , Josh Tois , Marc I Diamond , et al.
EMBO Molecular Medicine, 2020, 12 (12), pp.e12025. ⟨10.15252/emmm.202012025⟩
Journal articles pasteur-03132696v1
Image document

TspanC8 tetraspanins differentially regulate ADAM10 endocytosis and half-life

Etienne Eschenbrenner , Stéphanie Jouannet , Denis Clay , Joëlle Chaker , Claude Boucheix , et al.
Life Science Alliance, 2019, 3, pp.e201900444. ⟨10.26508/lsa.201900444⟩
Journal articles hal-02486001v1
Image document

Tunneling Nanotubes: The Fuel of Tumor Progression?

Giulia Pinto , Christel Brou , Chiara Zurzolo
Trends in Cancer, 2020, ⟨10.1016/j.trecan.2020.04.012⟩
Journal articles pasteur-02941638v1
Image document

Patient-derived glioblastoma stem cells transfer mitochondria through tunneling nanotubes in tumor organoids

Giulia Pinto , Inés Saenz-De-Santa-Maria , Patricia Chastagner , Emeline Perthame , Caroline Delmas , et al.
Biochemical Journal, 2021, 478 (1), pp.21-39. ⟨10.1042/BCJ20200710⟩
Journal articles pasteur-03167375v1
Image document

Monoubiquitination and endocytosis direct gamma-secretase cleavage of activated Notch receptor.

Neetu Gupta-Rossi , Emmanuelle Six , Odile Lebail , Frédérique Logeat , Patricia Chastagner , et al.
Journal of Cell Biology, 2004, 166 (1), pp.73-83. ⟨10.1083/jcb.200310098⟩
Journal articles pasteur-00583271v1
Image document

AIP4/Itch Regulates Notch Receptor Degradation in the Absence of Ligand

Patricia Chastagner , Alain Israel , Christel Brou
PLoS ONE, 2008, 3 (7), pp.e2735. ⟨10.1371/journal.pone.0002735⟩
Journal articles pasteur-00307917v1
Image document

TspanC8 tetraspanins differentially regulate the cleavage of ADAM10 substrates, Notch activation and ADAM10 membrane compartmentalization

Stéphanie Jouannet , Julien Saint-Pol , Laurent Fernandez , Viet Nguyen , Stéphanie Charrin , et al.
Cellular and Molecular Life Sciences, 2016, 73 (9), pp.1895 - 1915. ⟨10.1007/s00018-015-2111-z⟩
Journal articles inserm-01677606v1
Image document

The Ubiquitin specific protease 12 (USP12) is a negative regulator of Notch signaling acting on receptor trafficking towards degradation.

Julien Moretti , Patricia Chastagner , Chih-Chao Liang , Martin A. Cohn , Alain Israël , et al.
Journal of Biological Chemistry, 2012, 287, pp.29429-41. ⟨10.1074/jbc.M112.366807⟩
Journal articles pasteur-00717028v1

Endocytose et voie de signalisation Notch

Christel Brou , Frédérique Logeat
Médecine/Sciences, 2006, 22 (8-9), pp.685-8. ⟨10.1051/medsci/20062289685⟩
Journal articles pasteur-00162064v1

Itch/AIP4 mediates Deltex degradation through the formation of K29-linked polyubiquitin chains.

Patricia Chastagner , Alain Israël , Christel Brou
EMBO Reports, 2007, 7 (11), pp.1147-53. ⟨10.1038/sj.embor.7400822⟩
Journal articles pasteur-00162850v1