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authFullName_s : Caroline Demangel
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Mycobacterium leprae Phenolglycolipid-1 Expressed by Engineered M. bovis BCG Modulates Early Interaction with Human Phagocytes

Guillaume Tabouret , Catherine Astarie-Dequeker , Caroline Demangel , Wladimir Malaga , Patricia Constant , et al.
PLoS Pathogens, 2010, 6 (10), pp.e1001159. ⟨10.1371/journal.ppat.1001159⟩
Journal articles pasteur-01376090v1
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De novo synthesized polyunsaturated fatty acids operate as both host immunomodulators and nutrients for Mycobacterium tuberculosis

Thomas Laval , Laura Pedró-Cos , Wladimir Malaga , Laure Guenin-Macé , Alexandre Pawlik , et al.
eLife, 2021, 10, pp.e71946. ⟨10.7554/eLife.71946⟩
Journal articles pasteur-03534651v1
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The Sec61 translocon is a therapeutic vulnerability in multiple myeloma

Antoine Domenger , Caroline Choisy , Ludivine Baron , Véronique Mayau , Emeline Perthame , et al.
EMBO Molecular Medicine, 2022, Online ahead of print., pp.e14740. ⟨10.15252/emmm.202114740⟩
Journal articles pasteur-03534527v1
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Mycolactone diffuses into the peripheral blood of Buruli ulcer patients--implications for diagnosis and disease monitoring.

Fred S. Sarfo , Fabien Le Chevalier , N'Guetta Aka , Richard O. Phillips , Yaw Amoako , et al.
PLoS Neglected Tropical Diseases, 2011, 5 (7), pp.e1237. ⟨10.1371/journal.pntd.0001237⟩
Journal articles inserm-00691438v1
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Shaping mycolactone for therapeutic use against inflammatory disorders

Laure Guenin-Mace , Ludivine Baron , Anne-Caroline Chany , Cédric Tresse , Sarah Saint-Auret , et al.
Science Translational Medicine, 2015, 7 (289), pp.289ra85 - 289ra85. ⟨10.1126/scitranslmed.aab0458⟩
Journal articles pasteur-01382767v1
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Combined Inflammatory and Metabolic Defects Reflected by Reduced Serum Protein Levels in Patients with Buruli Ulcer Disease

Richard O. Phillips , Fred S. Sarfo , Jordi Landier , Reid Oldenburg , Michael Frimpong , et al.
PLoS Neglected Tropical Diseases, 2014, 8 (4), pp.e2786. ⟨10.1371/journal.pntd.0002786⟩
Journal articles pasteur-01384561v1
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The impact of gut microbiota on depressive-like behaviors and adult hippocampal neurogenesis requires the endocannabinoid system

Grégoire Chevalier , Eleni Siopi , Laure Guenin-Macé , Maud Pascal , Thomas Laval , et al.
Preprints, Working Papers, ... pasteur-02873657v1
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Mycolactone Purification from M. ulcerans Cultures and HPLC-Based Approaches for Mycolactone Quantification in Biological Samples

Aline Rifflet , Caroline Demangel , Laure Guenin-Macé
Mycobacterium ulcerans, 2387, Springer US, pp.117-130, 2021, Methods in Molecular Biology, 978-1-0716-1779-3. ⟨10.1007/978-1-0716-1779-3_13⟩
Book sections pasteur-03534701v1

Zika virus induces massive cytoplasmic vacuolization and paraptosis‐like death in infected cells

Blandine Monel , Alex Compton , Timothée Bruel , Sonia Amraoui , Julien Burlaud-Gaillard , et al.
EMBO Journal, 2017, 36 (12), pp.1653-1668. ⟨10.15252/embj.201695597⟩
Journal articles pasteur-03253584v1

Mycolactone suppresses T cell responsiveness by altering both early signaling and posttranslational events.

Sheerazed Boulkroun , Laure Guenin-Macé , Maria-Isabel Thoulouze , Marc Monot , Anaïs Merckx , et al.
Journal of Immunology, 2010, 184 (3), pp.1436-44. ⟨10.4049/jimmunol.0902854⟩
Journal articles pasteur-00594632v1
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Proteomic Analysis of the SH2Domain-containing Leukocyte Protein of 76 kDa (SLP76) Interactome

Yacine Bounab , Anne-Marie- Hesse , Bruno Iannascoli , Luca Grieco , Yohann Couté , et al.
Molecular and Cellular Proteomics, 2013, 12 (10), pp.2874-2889. ⟨10.1074/mcp.M112.025908⟩
Journal articles hal-02086260v1
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Antigen discovery: a postgenomic approach to leprosy diagnosis.

Romulo Aráoz , Nadine Honoré , Sungae Cho , Jong-Pill Kim , Sang-Nae Cho , et al.
Infection and Immunity, 2006, 74 (1), pp.175-82. ⟨10.1128/IAI.74.1.175-182.2006⟩
Journal articles pasteur-00204119v1
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Effect of gut microbiota on depressive-like behaviors in mice is mediated by the endocannabinoid system

Grégoire Chevalier , Eleni Siopi , Laure Guenin-Macé , Maud Pascal , Thomas Laval , et al.
Nature Communications, 2020, 11 (1), ⟨10.1038/s41467-020-19931-2⟩
Journal articles hal-03231388v1

Synthetic Variants of Mycolactone Bind and Activate Wiskott–Aldrich Syndrome Proteins

Anne-Caroline Chany , Romain Veyron-Churlet , Cédric Tresse , Véronique Mayau , Virginie Casarotto , et al.
Journal of Medicinal Chemistry, 2014, 57 (17), pp.7382 - 7395. ⟨10.1021/jm5008819⟩
Journal articles pasteur-03320888v1
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Spatiotemporal analysis of mycolactone distribution in vivo reveals partial diffusion in the central nervous system

Emma Colucci-Guyon , Aline Rifflet , Sarah Saint-Auret , Anaëlle da Costa , Laurent Boucontet , et al.
PLoS Neglected Tropical Diseases, 2020, 14 (12), pp.e0008878. ⟨10.1371/journal.pntd.0008878⟩
Journal articles pasteur-03046953v1
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Mycobacterial Phenolic Glycolipids Selectively Disable TRIF-Dependent TLR4 Signaling in Macrophages

Reid Oldenburg , Véronique Mayau , Jacques Prandi , Ainhoa Arbues , Catherine Astarie-Dequeker , et al.
Frontiers in Immunology, 2018, 9, 12 p. ⟨10.3389/fimmu.2018.00002⟩
Journal articles hal-02323696v1

Mycobacterium leprae pgl1 expression by BCG increases CR3 mediated entry into mouse myeloid cells and induces Syk/NFAT cytokine production

Emilie Doz-Deblauwe , Florence Carreras , Aude Remot , Mathieu Epardaud , Caroline Demangel , et al.
Journées d'Animation Scientifique du Département Santé Animale, Oct 2018, Nantes, France. , 2018, Santé Animale et Santé Publique
Conference poster hal-02736584v1

A Diverted Total Synthesis of Mycolactone Analogues: An Insight into Buruli Ulcer Toxins

Anne-Caroline Chany , Virginie Casarotto , Marjorie Schmitt , Céline Tarnus , Laure Guenin-Macé , et al.
Chemistry - A European Journal, 2011, 17 (51), pp.14413-14419. ⟨10.1002/chem.201102542⟩
Journal articles istex hal-02128753v1
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Sec61 blockade by mycolactone: A central mechanism in Buruli ulcer disease

Caroline Demangel , Stephen High
Biology of the Cell, 2018, 110 (11), pp.237-248. ⟨10.1111/boc.201800030⟩
Journal articles pasteur-03534760v1
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Host Immune-Metabolic Adaptations Upon Mycobacterial Infections and Associated Co-Morbidities

Alba Llibre , Martin Dedicoat , Julie Burel , Caroline Demangel , Matthew O’shea , et al.
Frontiers in Immunology, 2021, 12, pp.747387. ⟨10.3389/fimmu.2021.747387⟩
Journal articles pasteur-03903851v1

Lipids of Pathogenic Mycobacteria: Contributions to Virulence and Host Immune Suppression

Laure Guenin-Macé , Roxane Simeone , Caroline Demangel
Transboundary and emerging diseases, 2009, 56 (6-7), pp.255-268. ⟨10.1111/j.1865-1682.2009.01072.x⟩
Journal articles istex pasteur-02863010v1
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Ipomoeassin F Binds Sec61α to Inhibit Protein Translocation

Guanghui Zong , Zhijian Hu , Sarah O’keefe , Dale Tranter , Michael Iannotti , et al.
Journal of the American Chemical Society, 2019, 141 (21), pp.8450-8461. ⟨10.1021/jacs.8b13506⟩
Journal articles hal-02323236v1
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Metabolomic profiles delineate mycolactone signature in Buruli ulcer disease

Fatoumata Niang , Fred S. Sarfo , Michael Frimpong , Laure Guenin-Macé , Mark Wansbrough-Jones , et al.
Scientific Reports, 2015, 5, pp.17693 - 17693. ⟨10.1038/srep17693⟩
Journal articles pasteur-01383808v1
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Molecular Mechanisms Underpinning the Circulation and Cellular Uptake of Mycobacterium ulcerans Toxin Mycolactone

Bruno Tello Rubio , Florence Bugault , Blandine Baudon , Bertrand Raynal , Sébastien Brûlé , et al.
Frontiers in Pharmacology, 2021, 12, pp.733496. ⟨10.3389/fphar.2021.733496⟩
Journal articles hal-03358263v1
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Mycolactone impairs T cell homing by suppressing microRNA control of L-selectin expression.

Laure Guenin-Macé , Florent Carrette , François Asperti-Boursin , Agnès Le Bon , Laxmee Caleechurn , et al.
Proceedings of the National Academy of Sciences of the United States of America, 2011, 108 (31), pp.12833-8. ⟨10.1073/pnas.1016496108⟩
Journal articles pasteur-00738806v1

Nutrient-dependent regulation of β-cell proinsulin content

Xiaoxi Xu , Anoop Arunagiri , Maroof Alam , Leena Haataja , Charles R Evans , et al.
Journal of Biological Chemistry, 2023, pp.104836. ⟨10.1016/j.jbc.2023.104836⟩
Journal articles pasteur-04135046v1
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Defensive‐lipid droplets: Cellular organelles designed for antimicrobial immunity

Rémi Safi , Miguel Sánchez-Álvarez , Marta Bosch , Caroline Demangel , Robert G Parton , et al.
Immunological Reviews, 2023, pp.Online Version of Record before inclusion in an issue. ⟨10.1111/imr.13199⟩
Journal articles pasteur-04135560v1

Sec61 blockade by mycolactone inhibits antigen cross-presentation independently of endosome-to-cytosol export

Jeff E. Grotzke , Patrycja Kozik , Jean-David Morel , Francis Impens , Natalia Pietrosemoli , et al.
Proceedings of the National Academy of Sciences of the United States of America, 2017, 114 (29), pp.E5910-E5919. ⟨10.1073/pnas.1705242114⟩
Journal articles pasteur-03537029v1

Immunosuppressive Signature of Cutaneous Mycobacterium ulcerans Infection in the Peripheral Blood of Patients with Buruli Ulcer Disease

Richard Phillips , Fred s. Sarfo , Laure Guenin‐macé , Jérémie Decalf , Mark Wansbrough‐jones , et al.
Journal of Infectious Diseases, 2009, 200 (11), pp.1675 - 1684. ⟨10.1086/646615⟩
Journal articles pasteur-01402286v1
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Insights into the ancestry evolution of the Mycobacterium tuberculosis complex from analysis of Mycobacterium riyadhense

Qingtian Guan , Musa Garbati , Sara Mfarrej , Talal Almutairi , Thomas Laval , et al.
NAR Genomics and Bioinformatics, 2021, 3 (3), pp.lqab070. ⟨10.1093/nargab/lqab070⟩
Journal articles pasteur-03534725v1