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authFullName_s : Benoit Witkowski
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Keep the quality high: the benefits of lot testing for the quality control of malaria rapid diagnostic tests

Sandra Incardona , David Bell , Ana Campillo , Jane Cunningham , Frederic Ariey , et al.
Malaria Journal, 2020, 19 (1), pp.247. ⟨10.1186/s12936-020-03324-3⟩
Journal articles pasteur-03274278v1
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Plasmodium falciparum dihydroartemisinin-piperaquine failures in Cambodia are associated with mutant K13 parasites presenting high survival rates in novel piperaquine in vitro assays: retrospective and prospective investigations

Valentine Duru , Nimol Khim , Rithea Leang , Saorin Kim , Anais Domergue , et al.
BMC Medicine, 2015, 13 (1), pp.305. ⟨10.1186/s12916-015-0539-5⟩
Journal articles hal-02560638v1
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Clinical and In Vitro Resistance of Plasmodium falciparum to Artesunate-Amodiaquine in Cambodia

Mélissa Mairet-Khedim , Rithea Leang , Camille Marmai , Nimol Khim , Brigitte Izac , et al.
Clinical Infectious Diseases, 2021, 73 (3), pp.406-413. ⟨10.1093/cid/ciaa628⟩
Journal articles pasteur-03494757v1
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Studying Land Cover Changes in a Malaria-Endemic Cambodian District: Considerations and Constraints

Anaïs Pepey , Marc Souris , Amélie Vantaux , Serge Morand , Dysoley Lek , et al.
Remote Sensing, 2020, 12 (18), pp.2972. ⟨10.3390/RS12182972⟩
Journal articles hal-02986060v1
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Choosing interventions to eliminate forest malaria: preliminary results of two operational research studies inside Cambodian forests

Amber Kunkel , Chea Nguon , Sophea Iv , Srean Chhim , Dom Peov , et al.
Malaria Journal, 2021, 20 (1), pp.51. ⟨10.1186/s12936-020-03572-3⟩
Journal articles pasteur-03494756v1
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Single-cell RNA sequencing of Plasmodium vivax sporozoites reveals stage- and species-specific transcriptomic signatures

Anthony A Ruberto , Caitlin Bourke , Amélie Vantaux , Steven P Maher , Aaron Jex , et al.
PLoS Neglected Tropical Diseases, 2022, 16 (8), pp.e0010633. ⟨10.1371/journal.pntd.0010633⟩
Journal articles hal-03841102v1
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Plasmodium copy number variation scan: gene copy numbers evaluation in haploid genomes.

Johann Beghain , Anne-Claire Langlois , Eric Legrand , Laura Grange , Nimol Khim , et al.
Malaria Journal, 2016, 15 (1), pp.206. ⟨10.1186/s12936-016-1258-x⟩
Journal articles pasteur-01303621v1
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A molecular marker of artemisinin-resistant Plasmodium falciparum malaria.

Frédéric Ariey , Benoit Witkowski , Chanaki Amaratunga , Johann Beghain , Anne-Claire Langlois , et al.
Nature, 2014, 505 (7481), pp.50-5. ⟨10.1038/nature12876⟩
Journal articles pasteur-00921203v1
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Anopheles ecology, genetics and malaria transmission in northern Cambodia

Amélie Vantaux , Michelle M Riehle , Eakpor Piv , Elise J Farley , Sophy Chy , et al.
Scientific Reports, 2021, 11 (1), pp.6458. ⟨10.1038/s41598-021-85628-1⟩
Journal articles pasteur-03261884v1
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Artemisinin-independent inhibitory activity of Artemisia sp. infusions against different Plasmodium stages including relapse-causing hypnozoites

Kutub Ashraf , Shahin Tajeri , Christophe-Sébastien Arnold , Nadia Amanzougaghene , Jean-François Franetich , et al.
Life Science Alliance, 2021, 5 (3), pp.e202101237. ⟨10.26508/lsa.202101237⟩
Journal articles pasteur-03480928v2
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Cross-resistance of the chloroquine-derivative AQ-13 with amodiaquine in Cambodian Plasmodium falciparum isolates

Flore Nardella , Mélissa Mairet-Khedim , Camille Roesch , Steven P Maher , Sopheakvatey Ke , et al.
Journal of Antimicrobial Chemotherapy, 2021, 76 (10), pp.2565-2568. ⟨10.1093/jac/dkab219⟩
Journal articles pasteur-03480931v1

Induction of multidrug tolerance in plasmodium falciparum by extended artemisinin pressure

Sandie Ménard , Tanila Ben Haddou , Arba Pramundita Ramadani , F. Ariey , Xavier Iriart , et al.
Emerging Infectious Diseases, 2015, 21 (10), pp.1733-1741. ⟨10.3201/eid2110.150682⟩
Journal articles hal-01925135v1

Histone Methyltransferase Inhibitors Are Orally Bioavailable, Fast-Acting Molecules with Activity against Different Species Causing Malaria in Humans

Nicholas Malmquist , Sandeep Sundriyal , Joachim Caron , Patty Chen , Benoit Witkowski , et al.
Antimicrobial Agents and Chemotherapy, 2015, 59 (2), pp.950-959. ⟨10.1128/AAC.04419-14⟩
Journal articles hal-02560661v1
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DNA Methylation Bisubstrate Inhibitors Are Fast-Acting Drugs Active against Artemisinin-Resistant Plasmodium falciparum Parasites

Flore Nardella , Ludovic Halby , Elie Hammam , Diane Erdmann , Véronique Cadet-Daniel , et al.
ACS Central Science, 2020, 6 (1), pp.16-21. ⟨10.1021/acscentsci.9b00874⟩
Journal articles hal-02571983v1
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Mobility evaluation by GPS tracking in a rural, low-income population in Cambodia

Anaïs Pepey , Thomas Obadia , Saorin Kim , Siv Sovannaroth , Ivo Mueller , et al.
PLoS ONE, 2022, 17 (5), pp.e0266460. ⟨10.1371/journal.pone.0266460⟩
Journal articles pasteur-03669329v1
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Forest malaria in Cambodia: the occupational and spatial clustering of Plasmodium vivax and Plasmodium falciparum infection risk in a cross-sectional survey in Mondulkiri province, Cambodia

Mirco Sandfort , Amélie Vantaux , Saorin Kim , Thomas Obadia , Anaïs Pepey , et al.
Malaria Journal, 2020, 19 (1), pp.413. ⟨10.1186/s12936-020-03482-4⟩
Journal articles pasteur-03023631v1
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Global analysis of Plasmodium falciparum Na+/H+ exchanger (pfnhe-1) allele polymorphism and its usefulness as a marker of in vitro resistance to quinine

Didier Ménard , Valérie Andriantsoanirina , Nimol Khim , Arsène Ratsimbasoa , Benoit Witkowski , et al.
International Journal for Parasitology, 2013, 3, pp.8-19. ⟨10.1016/j.ijpddr.2012.10.001⟩
Journal articles hal-02560678v1
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In Silico screening on the three-dimensional model of the Plasmodium vivax SUB1 protease leads to the validation of a novel anti-parasite compound.

Anthony Bouillon , David Giganti , Christophe Benedet , Olivier Gorgette , Stéphane Pêtres , et al.
Journal of Biological Chemistry, 2013, 288, pp.18561-73. ⟨10.1074/jbc.M113.456764⟩
Journal articles pasteur-01457905v1

K13-propeller mutations confer artemisinin resistance in Plasmodium falciparum clinical isolates

Judith Straimer , Nina F. Gnadig , Benoit Witkowski , Chanaki Amaratunga , Valentine Duru , et al.
Science, 2015, 347 (6220), pp.428-431. ⟨10.1126/science.1260867⟩
Journal articles hal-01925134v1
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Hemisynthetic alkaloids derived from trilobine are antimalarials with sustained activity in multidrug-resistant Plasmodium falciparum

Flore Nardella , Irina Dobrescu , Haitham Hassan , Fabien Rodrigues , Sabine Thiberge , et al.
iScience, 2023, 26 (2), pp.105940. ⟨10.1016/j.isci.2023.105940⟩
Journal articles pasteur-04099097v1
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Amplification of Duffy binding protein-encoding gene allows Plasmodium vivax to evade host anti-DBP humoral immunity

Jean Popovici , Camille Roesch , Lenore L. Carias , Nimol Khim , Saorin Kim , et al.
Nature Communications, 2020, 11 (1), pp.953. ⟨10.1038/s41467-020-14574-9⟩
Journal articles pasteur-03494795v1

A Worldwide Map of Plasmodium falciparum K13-Propeller Polymorphisms.

Didier Ménard , Nimol Khim , Johann Beghain , Ayola A Adegnika , Mohammad Shafiul-Alam , et al.
New England Journal of Medicine, 2016, 374 (25), pp.2453-64. ⟨10.1056/NEJMoa1513137⟩
Journal articles pasteur-01336483v1

Efficacy of dihydroartemisinin/piperaquine in patients with noncomplicated Plasmodium falciparum malaria in Yaoundé, Cameroon

Mélissa Mairet-Khedim , Sandrine Nsango , Christelle Ngou , Sandie Menard , Camille Roesch , et al.
Journal of Antimicrobial Chemotherapy, 2021, 76 (11), pp.3037-3044. ⟨10.1093/jac/dkab281⟩
Journal articles pasteur-03494748v1
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Impact of the first-line treatment shift from dihydroartemisinin/piperaquine to artesunate/mefloquine on Plasmodium vivax drug susceptibility in Cambodia

Camille Roesch , Mélissa Mairet-Khedim , Saorin Kim , Dysoley Lek , Jean Popovici , et al.
Journal of Antimicrobial Chemotherapy, 2020, 75 (7), pp.1766-1771. ⟨10.1093/jac/dkaa092⟩
Journal articles pasteur-03494789v1
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A surrogate marker of piperaquine-resistant Plasmodium falciparum malaria: a phenotype–genotype association study

Benoit Witkowski , Valentine Duru , Nimol Khim , Leila S Ross , Benjamin Saintpierre , et al.
The Lancet Infectious Diseases, 2016, 17 (2), pp.174-183. ⟨10.1016/S1473-3099(16)30415-7⟩
Journal articles pasteur-01400955v1
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Whole genome sequencing of field isolates reveals a common duplication of the Duffy binding protein gene in Malagasy Plasmodium vivax strains.

Didier Menard , Ernest R Chan , Christophe Benedet , Arsène Ratsimbasoa , Saorin Kim , et al.
PLoS Neglected Tropical Diseases, 2013, 7 (11), pp.e2489. ⟨10.1371/journal.pntd.0002489⟩
Journal articles pasteur-01109627v1
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Emerging Southeast Asian PfCRT mutations confer Plasmodium falciparum resistance to the first-line antimalarial piperaquine

Leila Ross , Satish Dhingra , Sachel Mok , Tomas Yeo , Kathryn Wicht , et al.
Nature Communications, 2018, 9 (1), pp.3314. ⟨10.1038/s41467-018-05652-0⟩
Journal articles hal-02558701v1
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Procainamide-SAHA fused inhibitors of hHDAC6 tackle multi-drug resistant malaria parasites

Flore Nardella , Ludovic Halby , Irina Dobrescu , Johanna Viluma , Corentin Bon , et al.
Journal of Medicinal Chemistry, 2021, 64 (14), pp.10403-10417. ⟨10.1021/acs.jmedchem.1c00821⟩
Journal articles hal-03264653v1
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Focused Screening and Treatment (FSAT): A PCR-Based Strategy to Detect Malaria Parasite Carriers and Contain Drug Resistant P. falciparum, Pailin, Cambodia.

Stefan Hoyer , Sokomar Nguon , Saorin Kim , Najibullah Habib , Nimol Khim , et al.
PLoS ONE, 2012, 7 (10), pp.e45797. ⟨10.1371/journal.pone.0045797⟩
Journal articles pasteur-00741087v1
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Whole Genome Sequencing of Field Isolates Provides Robust Characterization of Genetic Diversity in Plasmodium vivax.

Ernest R Chan , Didier Menard , Peter H David , Arsène Ratsimbasoa , Saorin Kim , et al.
PLoS Neglected Tropical Diseases, 2012, 6 (9), pp.e1811. ⟨10.1371/journal.pntd.0001811⟩
Journal articles pasteur-00741089v1