Allosteric activation of Bordetella pertussis adenylyl cyclase by calmodulin: molecular dynamics and mutagenesis studies.
Edithe Selwa
,
Marilyne Davi
,
Alexandre Chenal
,
Ana-Cristina Sotomayor-Pérez
,
Daniel Ladant
,
et al.
Journal articles
pasteur-01107494v1
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Deciphering Membrane Insertion of the Diphtheria Toxin T Domain by Specular Neutron Reflectometry and Solid-State NMR Spectroscopy
Alexandre Chenal
,
Lydia Prongidi-Fix
,
Aurélie Perier
,
Chistopher Aisenbrey
,
Grégory Vernier
,
et al.
Journal articles
istex
hal-01151673v1
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Type III secretion effectors of the IpaH family are E3 ubiquitin ligases.
John R Rohde
,
Ashton Breitkreutz
,
Alexandre Chenal
,
Philippe Sansonetti
,
Claude Parsot
Journal articles
pasteur-01540876v1
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Calmodulin-induced conformational and hydrodynamic changes in the catalytic domain of Bordetella pertussis adenylate cyclase toxin.
Johanna C Karst
,
Ana Cristina Sotomayor Pérez
,
J Iñaki Guijarro
,
Bertrand Raynal
,
Alexandre Chenal
,
et al.
Journal articles
hal-00512114v1
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Membrane Interaction of Botulinum Neurotoxin A Translocation (T) Domain THE BELT REGION IS A REGULATORY LOOP FOR MEMBRANE INTERACTION
Marie Galloux
,
Heidi Vitrac
,
Caroline Montagner
,
Stephanie Raffestin
,
Michel R. Popoff
,
et al.
Journal articles
hal-01187636v1
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The Adenylate Cyclase (CyaA) Toxin from Bordetella pertussis Has No Detectable Phospholipase A (PLA) Activity In Vitro
Alexis Voegele
,
Mirko Sadi
,
Dorothée Raoux-Barbot
,
Thibaut Douche
,
Mariette Matondo
,
et al.
Journal articles
pasteur-02329482v1
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Bioengineering of Bordetella pertussis Adenylate Cyclase Toxin for Antigen-Delivery and Immunotherapy
Alexandre Chenal
,
Daniel Ladant
Journal articles
pasteur-02565647v1
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Cellular functions and X-ray structure of anthrolysin O, a cholesterol-dependent cytolysin secreted by Bacillus anthracis
Raymond W Bourdeau
,
Enrico Malito
,
Alexandre Chenal
,
Brian L Bishop
,
Mark W Musch
,
et al.
Journal articles
pasteur-01540766v1
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From bulk to plasmonic nanoparticle surfaces: the behavior of two potent therapeutic peptides, octreotide and pasireotide
Belén Hernández
,
Eduardo López-Tobar
,
Santiago Sanchez-Cortes
,
Yves-Marie Coïc
,
Bruno Baron
,
et al.
Journal articles
pasteur-01378668v1
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A Robust and Sensitive Spectrophotometric Assay for the Enzymatic Activity of Bacterial Adenylate Cyclase Toxins
Marilyne Davi
,
Mirko Sadi
,
Irene Pitard
,
Alexandre Chenal
,
Daniel Ladant
Journal articles
hal-03858756v1
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Hydrogen/Deuterium Exchange Mass Spectrometry for the Structural Analysis of Detergent-Solubilized Membrane Proteins
Darragh O’brien
,
Véronique Hourdel
,
Alexandre Chenal
,
Sébastien Brier
Springer.
Expression, Purification, and Structural Biology of Membrane Proteins , 2127, Humana, New York, NY, pp.339-358, 2020, Methods in Molecular Biology, 978-1-0716-0372-7.
⟨10.1007/978-1-0716-0373-4_22⟩
Book sections
pasteur-02559306v1
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Post-translational acylation controls the folding and functions of the CyaA RTX toxin
Darragh O'Brien
,
Sara E Cannella
,
Alexis Voegele
,
Dorothée Raoux-Barbot
,
Marilyne Davi
,
et al.
Journal articles
pasteur-02330713v1
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A High‐Affinity Calmodulin‐Binding Site in the CyaA Toxin Translocation Domain is Essential for Invasion of Eukaryotic Cells
Alexis Voegele
,
Mirko Sadi
,
Darragh Patrick O'Brien
,
Pauline Gehan
,
Dorothée Raoux‐barbot
,
et al.
Journal articles
pasteur-03211832v1
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Post-translational acylation controls the folding and functions of the CyaA RTX toxin
Darragh P O'Brien
,
Sara E Cannella
,
Alexis Voegele
,
Dorothée Raoux-Barbot
,
Maryline Davi
,
et al.
2021
Preprints, Working Papers, ...
pasteur-03221015v1
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Dissecting the Structural and Chemical Determinants of the “Open-to-Closed” Motion in the Mannosyltransferase PimA from Mycobacteria
Ane Rodrigo-Unzueta
,
Mattia Ghirardello
,
Saioa Urresti
,
Ignacio Delso
,
David Giganti
,
et al.
Journal articles
pasteur-03210105v1
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Functional and structural consequences of epithelial cell invasion by Bordetella pertussis adenylate cyclase toxin
Christelle Angely
,
Daniel Ladant
,
Emmanuelle Planus
,
Bruno Louis
,
Marcel Filoche
,
et al.
Journal articles
inserm-02893474v1
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Translocation and calmodulin-activation of the adenylate cyclase toxin (CyaA) of Bordetella pertussis
Alexis Voegele
,
Darragh P. O'Brien
,
Orso Subrini
,
Nicolas Sapay
,
Sara E. Cannella
,
et al.
Journal articles
hal-02184809v1
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Clostridium septicum alpha-toxin forms pores and induces rapid cell necrosis.
Oliver Knapp
,
Elke Maier
,
Sanae Ben Mkaddem
,
Roland Benz
,
Marcelle Bens
,
et al.
Journal articles
pasteur-01509604v1
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Disorder-to-Order Transition in the CyaA Toxin RTX Domain: Implications for Toxin Secretion
Ana-Cristina Sotomayor-Pé
,
Daniel Ladant
,
Alexandre Chenal
Journal articles
pasteur-01132650v1
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Membrane-Active Properties of an Amphitropic Peptide from the CyaA Toxin Translocation Region
Alexis Voegele
,
Orso Subrini
,
Nicolas Sapay
,
Daniel Ladant
,
Alexandre Chenal
Journal articles
pasteur-02882330v1
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Development of Conformational Antibodies to Detect Bcl-xL's Amyloid Aggregates in Metal-Induced Apoptotic Neuroblastoma Cells
Alexis Gonneaud
,
Fatima-Zohra Fakhir
,
Emeline Landas
,
Enora Le Tallec
,
Elisabeth Chartier-Garcia
,
et al.
Journal articles
hal-03031819v1
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SEC-SAXS and HDX-MS: A powerful combination. The case of the calcium-binding domain of a bacterial toxin
Darragh O'Brien
,
Sebastien Brier
,
Daniel Ladant
,
Dominique Durand
,
Alexandre Chenal
,
et al.
Journal articles
hal-02329435v1
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Characterization of the regions involved in the calcium-induced folding of the intrinsically disordered RTX motifs from the bordetella pertussis adenylate cyclase toxin.
Ana-Cristina Sotomayor Pérez
,
Johanna C Karst
,
Marilyne Davi
,
J Iñaki Guijarro
,
Daniel Ladant
,
et al.
Journal articles
hal-00512116v1
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Amyloid Fibrils Formed by the Programmed Cell Death Regulator Bcl-xL.
Alexandre Chenal
,
Charlotte Vendrely
,
Heidi Vitrac
,
Johanna C Karst
,
Alexis Gonneaud
,
et al.
Journal articles
pasteur-00654783v1
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Calmodulin fishing with a structurally disordered bait triggers CyaA catalysis
Darragh P. O'Brien
,
Dominique Durand
,
Alexis Voegele
,
Véronique Hourdel
,
Marilyne Davi
,
et al.
Journal articles
hal-02294928v1
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Calcium-dependent disorder-to-order transitions are central to the secretion and folding of the CyaA toxin of Bordetella pertussis, the causative agent of whooping cough
Darragh P. O'Brien
,
Ana Cristina Sotomayor Perez
,
Johanna Karst
,
Sara E. Cannella
,
Véronique Yvette Ntsogo Enguéné
,
et al.
Journal articles
hal-02183106v1
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Structural models of intrinsically disordered and calcium-bound folded states of a protein adapted for secretion
Darragh P. O’brien
,
Belen Hernandez
,
Dominique Durand
,
Véronique Hourdel
,
Ana-Cristina Sotomayor-Pérez
,
et al.
Journal articles
pasteur-01406897v1
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The Translocation Domain of Botulinum Neurotoxin A Moderates the Propensity of the Catalytic Domain to Interact with Membranes at Acidic pH
Anne Araye
,
Amélie Goudet
,
Julien Barbier
,
Sylvain Pichard
,
Bruno Baron
,
et al.
Journal articles
pasteur-01378747v1
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MEMHDX: An interactive tool to expedite the statistical validation and visualization of large HDX-MS datasets
Véronique Hourdel
,
Stevenn Volant
,
Darragh P. O'Brien
,
Alexandre Chenal
,
Julia Chamot-Rooke
,
et al.
Journal articles
pasteur-01377055v1
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Anchoring Sites of Fibrillogenic Peptide Hormone Somatostatin-14 on Plasmonic Nanoparticles
Eduardo López-Tobar
,
Belén Hernández
,
Johanna Gómez
,
Alexandre Chenal
,
José Vicente Garcia-Ramos
,
et al.
Journal articles
pasteur-01406738v1
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