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authFullName_s : Ahmed Haouz
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A High‐Affinity Calmodulin‐Binding Site in the CyaA Toxin Translocation Domain is Essential for Invasion of Eukaryotic Cells

Alexis Voegele , Mirko Sadi , Darragh Patrick O'Brien , Pauline Gehan , Dorothée Raoux‐barbot , et al.
Advanced Science, 2021, pp.2003630. ⟨10.1002/advs.202003630⟩
Journal articles pasteur-03211832v1
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Crystallographic studies of two variants of Pseudomonas aeruginosa IMPDH with impaired allosteric regulation

Gilles Labesse , Thomas Alexandre , Muriel Gelin , Ahmed Haouz , Hélène Munier-Lehmann
Acta crystallographica Section D : Structural biology [1993-..], 2015, 71, pp.1890-1899. ⟨10.1107/S1399004715013115⟩
Journal articles istex pasteur-01197071v1
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An extracellular Leptospira interrogans leucine‐rich repeat protein binds human E‐ and VE‐cadherins

Azad Eshghi , Robert A. Gaultney , Patrick England , Sébastien Brûlé , Isabelle Miras , et al.
Cellular Microbiology, 2019, 21 (2), pp.e12949. ⟨10.1111/cmi.12949⟩
Journal articles pasteur-02548693v1
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Insight into the role of the Bateman domain at the molecular and physiological levels through engineered IMPDHs

Antoine Gedeon , Nour Ayoub , Sébastien Brûlé , Bertrand Raynal , Gouzel Karimova , et al.
Protein Science, In press, pp.e4703. ⟨10.1002/pro.4703⟩
Journal articles pasteur-04164361v1
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Trypanosoma brucei RRP44: a versatile enzyme for processing structured and non-structured RNA substrates

Giovanna Cesaro , Heloisa Tramontin da Soler , Eloise Pavão Guerra-Slompo , Ahmed Haouz , Pierre Legrand , et al.
Nucleic Acids Research, 2023, 51 (1), pp.380-395. ⟨10.1093/nar/gkac1199⟩
Journal articles pasteur-03980368v1

Structural basis for the allosteric inhibition of UMP kinase from Gram‐positive bacteria, a promising antibacterial target

Patrick Walter , Ariel E Mechaly , Julien Bous , Ahmed Haouz , Patrick England , et al.
FEBS Journal, 2022, 289 (16), pp.4869-4887. ⟨10.1111/febs.16393⟩
Journal articles pasteur-04096367v1
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Crystal structure of a monoclonal antibody directed against an antigenic determinant common to Ogawa and Inaba serotypes of Vibrio cholerae O1.

Firoz Ahmed , Gwenaëlle André-Leroux , Ahmed Haouz , Alain Boutonnier , Muriel Delepierre , et al.
Proteins - Structure, Function and Bioinformatics, 2008, 70 (1), pp.284-8. ⟨10.1002/prot.21609⟩
Journal articles pasteur-00366238v1
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Evolution of abiotic cubane chemistries in a nucleic acid aptamer allows selective recognition of a malaria biomarker

Yee-Wai Cheung , Pascal Röthlisberger , Ariel E Mechaly , Patrick Weber , Fabienne Levi-Acobas , et al.
Proceedings of the National Academy of Sciences of the United States of America, 2020, 117 (29), pp.16790-16798. ⟨10.1073/pnas.2003267117⟩
Journal articles pasteur-03138380v1

The crystal structure of Rv2991 from Mycobacterium tuberculosis: An F420 binding protein with unknown function

Stefano Benini , Ahmed Haouz , Florence Proux , Pedro Alzari , Keith Wilson
Journal of Structural Biology, 2019, 206 (2), pp.216-224. ⟨10.1016/j.jsb.2019.03.006⟩
Journal articles pasteur-03095980v1
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3D structures of the Plasmodium vivax subtilisin-like drug target SUB1 reveal conformational changes to accommodate a substrate-derived α-ketoamide inhibitor

Mariano Martinez , Fernando A Batista , Manon Maurel , Anthony Bouillon , Laura Ortega Varga , et al.
Acta crystallographica Section D : Structural biology [1993-..], 2023, 79 (8), ⟨10.1107/s2059798323004710⟩
Journal articles pasteur-04158872v1

DARPin-assisted crystallography of the CC2-LZ domain of NEMO reveals a coupling between dimerization and ubiquitin binding.

Olivera Grubisha , Monika Kaminska , Stéphane Duquerroy , Elisabeth Fontan , Florence Cordier , et al.
Journal of Molecular Biology, 2010, 395 (1), pp.89-104. ⟨10.1016/j.jmb.2009.10.018⟩
Journal articles istex hal-00512126v1

Crystal structure of Mycobacterium tuberculosis LppA, a lipoprotein confined to pathogenic mycobacteria.

Martin Graña , Marco Bellinzoni , Jacques Bellalou , Ahmed Haouz , Isabelle Miras , et al.
Proteins - Structure, Function and Bioinformatics, 2010, 78 (3), pp.769-72. ⟨10.1002/prot.22603⟩
Journal articles istex pasteur-00508937v1
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Structure and function of the Leptospira interrogans peroxide stress regulator (PerR), an atypical PerR devoid of a structural metal-binding site

Mounira Kebouchi , Frederick Saul , Raleb Taher , Annie Landier , Bénédicte Beaudeau , et al.
Journal of Biological Chemistry, 2018, 293 (2), pp.497-509. ⟨10.1074/jbc.M117.804443⟩
Journal articles pasteur-02548922v1

Crystal Structure of the Extracellular Domain of a Bacterial Ligand-Gated Ion Channel

Hugues Nury , Nicolas Bocquet , Chantal Le Poupon , Bertrand Raynal , Ahmed Haouz , et al.
Journal of Molecular Biology, 2010, 395 (5), pp.1114-1127. ⟨10.1016/j.jmb.2009.11.024⟩
Journal articles pasteur-02174748v1
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DNA-binding mechanism and evolution of replication protein A

Clément Madru , Markel Martínez-Carranza , Sébastien Laurent , Alessandra Alberti , Maelenn Chevreuil , et al.
Nature Communications, 2023, 14 (1), pp.2326. ⟨10.1038/s41467-023-38048-w⟩
Journal articles hal-04112308v1
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Recognition determinants of broadly neutralizing human antibodies against dengue viruses.

Alexander Rouvinski , Pablo Guardado-Calvo , Giovanna Barba-Spaeth , Stéphane Duquerroy , Marie-Christine Vaney , et al.
Nature, 2015, 520 (7545), pp.109-113. ⟨10.1038/nature14130⟩
Journal articles hal-01148962v1
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A step-by-step in crystallo guide to bond cleavage and 1,6-anhydro-sugar product synthesis by a peptidoglycan-degrading lytic transglycosylase

Allison H Williams , Richard Wheeler , Lesly Rateau , Christian Malosse , Julia Chamot-Rooke , et al.
Journal of Biological Chemistry, 2018, 293 (16), pp.6000-6010. ⟨10.1074/jbc.ra117.001095⟩
Journal articles pasteur-01950858v1

Enzymatic and structural analysis of inhibitors designed against Mycobacterium tuberculosis thymidylate kinase. New insights into the phosphoryl transfer mechanism.

Ahmed Haouz , Veerle Vanheusden , Hélène Munier-Lehmann , Mattheus Froeyen , Piet Herdewijn , et al.
Journal of Biological Chemistry, 2003, 278 (7), pp.4963-71. ⟨10.1074/jbc.M209630200⟩
Journal articles pasteur-00167043v1

Purification, crystallization and preliminary X-ray characterization ofBacillus cereusarylamineN-acetyltransferase 3 [(BACCR)NAT3]

Xavier Kubiak , Benjamin Pluvinage , Inès Li de La Sierra-Gallay , Patrick Weber , Ahmed Haouz , et al.
Acta Crystallographica Section F: Structural Biology and Crystallization Communications, 2012, 68 (2), pp.196 - 198. ⟨10.1107/s1744309111053942⟩
Journal articles pasteur-03525338v1
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The epitope arrangement on flavivirus particles contributes to Mab C10’s extraordinary neutralization breadth across Zika and dengue viruses

Arvind Sharma , Xiaokang Zhang , Wanwisa Dejnirattisai , Xinghong Dai , Danyang Gong , et al.
Cell, 2021, 184 (25), pp.6052-6066.e18. ⟨10.1016/j.cell.2021.11.010⟩
Journal articles pasteur-03524447v1
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Structural snapshots along the reaction mechanism of the atypical poplar thioredoxin-like2.1.

Kamel Chibani , Frederick Saul , Claude Didierjean , Nicolas Rouhier , Ahmed Haouz
FEBS Letters, 2018, 592 (6), pp.1030-1041. ⟨10.1002/1873-3468.13009⟩
Journal articles hal-01844909v1
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PLA2G1B is involved in CD4 anergy and CD4 lymphopenia in HIV-infected patients

Julien Pothlichet , Thierry Rose , Florence Bugault , Louise Jeammet , Annalisa Meola , et al.
Journal of Clinical Investigation, 2020, 130 (6), pp.2872-2887. ⟨10.1172/JCI131842⟩
Journal articles hal-03091750v1

Nucleotide binding to human UMP-CMP kinase using fluorescent derivatives - a screening based on affinity for the UMP-CMP binding site.

Dimitri Topalis , Hiroki Kumamoto , Maria-Fernanda Amaya Velasco , Laurence Dugué , Ahmed Haouz , et al.
FEBS Journal, 2007, 274 (14), pp.3704-14. ⟨10.1111/j.1742-4658.2007.05902.x⟩
Journal articles pasteur-00166127v1
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New insight into flavivirus maturation from structure/function studies of the yellow fever virus envelope protein complex

E. Crampon , E. Covernton , M. Vaney , M. Dellarole , S. Sommer , et al.
Journal articles pasteur-04188597v1

In the Absence of Thioredoxins, What Are the Reductants for Peroxiredoxins in Thermotoga maritima?

Jérémy Couturier , Pascalita Prosper , Alison Winger-Mendes , Arnaud Hecker , Masakazu Hirasawa , et al.
Antioxidants and Redox Signaling, 2013, 18 (13), pp.1613 - 1622. ⟨10.1089/ars.2012.4739⟩
Journal articles hal-01268123v1
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Designed mono- and di-covalent inhibitors trap modeled functional motions for Trypanosoma cruzi proline racemase in crystallography

Patricia de Aguiar Amaral , Delphine Autheman , Guilherme Dias de Melo , Nicolas Gouault , Jean-François Cupif , et al.
PLoS Neglected Tropical Diseases, 2018, 12 (10), ⟨10.1371/journal.pntd.0006853⟩
Journal articles hal-01935360v1

Mycobacterium tuberculosis thymidylate kinase: structural studies of intermediates along the reaction pathway.

Emanuela Fioravanti , Ahmed Haouz , Thomas Ursby , Hélène Munier-Lehmann , Marc Delarue , et al.
Journal of Molecular Biology, 2003, 327 (5), pp.1077-92. ⟨10.1016/S0022-2836(03)00202-X⟩
Journal articles istex pasteur-00167041v1

The crystal structure of Trypanosoma cruzi arginine kinase

Pablo Fernandez , Ahmed Haouz , Claudio A. Pereira , Carlos Aguilar , Pedro M. Alzari
Proteins - Structure, Function and Bioinformatics, 2007, 69 (1), pp.209-212. ⟨10.1002/prot.21557⟩
Journal articles istex pasteur-03139224v1

The crystal structure of M. leprae ML2640c defines a large family of putative S-adenosylmethionine-dependent methyltransferases in mycobacteria.

Martin Graña , Ahmed Haouz , Alejandro Buschiazzo , Isabelle Miras , Annemarie Wehenkel , et al.
Protein Science, 2007, 16 (9), pp.1896-904. ⟨10.1110/ps.072982707⟩
Journal articles pasteur-00508941v1

Database searching for thymidine and thymidylate kinase inhibitors using three-dimensional structure-based methods.

David T Manallack , Mark R Sanderson , Maninder Sohi , Frank Wien , Helene Munier-Lehmann , et al.
Journal of Enzyme Inhibition and Medicinal Chemistry, 2002, 17 (3), pp.167-74. ⟨10.1080/14756360290032949⟩
Journal articles pasteur-00167044v1