Gram-scale synthesis of luciferins derived from coelenterazine and original insights into their bioluminescence properties - Institut Pasteur Access content directly
Journal Articles Organic & Biomolecular Chemistry Year : 2019

Gram-scale synthesis of luciferins derived from coelenterazine and original insights into their bioluminescence properties

Abstract

An original gram-scale synthesis of O-acetylated forms of coelenterazine, furimazine or hydroxy-bearing analogues of luciferins is described. The comparison over two hours of their bioluminescence, using the nanoKAZ/NanoLuc luciferase, provides remarkable insights useful for the selection of a substrate adapted for a given application.
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pasteur-02072739 , version 1 (23-10-2019)

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Eloi Coutant, Sophie Goyard, Vincent Hervin, Glwadys Gagnot, Racha Baatallah, et al.. Gram-scale synthesis of luciferins derived from coelenterazine and original insights into their bioluminescence properties. Organic & Biomolecular Chemistry, 2019, 15, ⟨10.1039/c9ob00459a⟩. ⟨pasteur-02072739⟩
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